Results 91 to 100 of about 4,042,650 (303)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Putting Africa on the Black Death map: Narratives from genetics and history
Afriques, 2018 Did the Black Death, the famous, devastating plague pandemic that struck the Mediterranean and Western Europe in the mid-14th century and seeded new strains of the pathogen, Yersinia pestis, in new locales, also reach Sub-Saharan Africa?
Monica H. Green
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Revista Brasileira de Política Internacional, 2018 This paper analyzes the internationalization of the Brazilian agricultural sector through a “global history” approach. The goal of the paper is to understand the internationalization of agribusiness as a smaller part of a transformation in the global ...
Helder Ferreira do Vale
doaj +1 more source
The North Atlantic alliance and collective defense at 70: confession and response revisited [PDF]
, 2019 The North Atlantic Treaty was largely a response to global sentiment that other international organizations, namely the United Nations, were not accomplishing their intended purpose of the maintenance and promotion of peace and order in the world.
Schmitt, Michael
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Global History: Opportunities, Dangers, Recent Trends
Culture & History Digital Journal, 2012 In contrast to national historical approaches, global history responds to the cultural and intellectual needs of communities, societies and cultures are increasingly interconnected. Global history is an appropriate way of looking to “our past”, in an era
Jürgen Kocka
doaj +1 more source
Global history, the emergence of chaos and inducing sustainability in networks of socio-ecological systems. [PDF]
PLoS One, 2023 Roman S, Bertolotti F.
europepmc +1 more source
The Global Risks Report 2016, 11th Edition [PDF]
, 2016 Now in its 11th edition, The Global Risks Report 2016 draws attention to ways that global risks could evolve and interact in the next decade. The year 2016 marks a forceful departure from past findings, as the risks about which the Report has been ...
core
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source