Results 71 to 80 of about 887,841 (265)
Global History: Opportunities, Dangers, Recent Trends
Culture & History Digital Journal, 2012 In contrast to national historical approaches, global history responds to the cultural and intellectual needs of communities, societies and cultures are increasingly interconnected. Global history is an appropriate way of looking to “our past”, in an era
Jürgen Kocka
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Global history, the emergence of chaos and inducing sustainability in networks of socio-ecological systems. [PDF]
PLoS One, 2023 Roman S, Bertolotti F.
europepmc +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Three Network Dynamics in Iran: A McLuhanian Account
International Journal of Communication, 2018 This article offers a new macrohistorical model of telecommunication and social relations with a focus on Iran as a case study. It shows how networks, as complex interacting forms of social associations, undergo historical changes through developments ...
Mehdi Mohsenian-Rad, Babak Rahimi
doaj
Globalization and Global History
Calenda, 2013 Because Globalization has become a conceptual problem and the source of epistemological discussions in almost all social sciences and humanities, this international workshop aims at questioning the changes (in scales, temporality) of historical research (or research on history) from different disciplinary viewpoints: sociology, history, anthropology ...
openaire +1 more source
The Electrophoretic Revolution in the 1960s: Historical Epistemology Meets the Global History of Science and Technology. [PDF]
Ber Wiss, 2022 Suárez-Díaz E.
europepmc +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source