Results 71 to 80 of about 4,042,650 (303)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Queerness—What Would the Queers Do? Analytical Concepts, Fluidity, and the Potential of Queer Semantic Fields for Global History

Cromohs: Cyber Review of Modern Historiography
In this essay, Sébastien Tremblay explores the potential of queerness as an analytical concept in the context of writing a global history of sexualities.
Sébastien Tremblay
doaj   +1 more source

Contre une vision diffusionniste de la « naissance de la prison »

Socio, 2020
During the “long” 19th century, the prison became the dominant institution of punishment on a worldwide scale. Focussing on the first half of this period, the article demonstrates that concepts of diffusion, which continue to provide the central model of
Stephan Scheuzger
doaj   +1 more source

Trauma and Trichotillomania: A Tenuous Relationship [PDF]

, 2016
Some have argued that hair pulling in trichotillomania (TTM) is triggered by traumatic events, but reliable evidence linking trauma to TTM is limited.
Compton, Scott N., Franklin, Martin E., Houghton, David C., Mathew, Abel S., Neal-Barnett, Angela M., Saunders, Stephen M., Twohig, Michael P., Woods, Douglas W.   +7 more
core   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Conexiones transnacionales: agentes encubiertos y tráfico de mujeres en los años 1920

Nuevo mundo - Mundos Nuevos, 2014
Este artículo examina una serie de diálogos entre un agente secreto y un propietario de casas de prostitución en la Buenos Aires de los años veinte. El argumento central es que los encuentros entre estos dos hombres contribuyeron a delinear las rutas de ...
Cristiana Schettini
doaj   +1 more source

The Global History of Corporate Governance: An Introduction [PDF]

This paper presents a synopsis of recent NBER studies of the history of corporate governance in Canada, China, France, Germany, Japan, India, Italy, the Netherlands, Sweden, the United Kingdom, and the United States.
Lloyd Steier, Randall K. Morck
core  

BPGrad: Towards Global Optimality in Deep Learning via Branch and Pruning

, 2017
Understanding the global optimality in deep learning (DL) has been attracting more and more attention recently. Conventional DL solvers, however, have not been developed intentionally to seek for such global optimality.
Wang, Guanghui, Wu, Yuanwei, Zhang, Ziming   +2 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Zika virus: New clinical syndromes and its emergence in the western hemisphere [PDF]

, 2016
Zika virus (ZIKV) had remained a relatively obscure flavivirus until a recent series of outbreaks accompanied by unexpectedly severe clinical complications brought this virus into the spotlight as causing an infection of global public health concern.
Brazilian Medical Genetics Society–Zika Embryopathy Task Force, Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, Collaborative Cross Consortium, European Centre for Disease Prevention and Control, European Centre for Disease Prevention and Control, Helen M. Lazear, Michael S. Diamond, T. C. Pierson   +9 more
core   +3 more sources