Results 101 to 110 of about 1,746,259 (365)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Hybrid photovoltaic-thermoelectric generator powered synchronous reluctance motor for pumping applications [PDF]

, 2019
The interest in photovoltaic (PV) pumping systems has increased, particularly in rural areas where there is no grid supply available. However, both the performance and the cost of the whole system are still an obstacle for a wide spread of this ...
Al-Dahifallah, Mujahed, Ibrahim, Mohamed Nabil Fathy, Rezk, Hegazy, Sergeant, Peter   +3 more
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Application of pattern search method to power system valve-point economic load dispatch

, 2007
Direct search (DS) methods are evolutionary algorithms used to solve constrained optimization problems. DS methods do not require any information about the gradient of the objective function at hand, while searching for an optimum solution.
AL-Othman, A.K., Al-Sumait, J.S., Sykulski, J.K.   +2 more
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

MPPT of a Photovoltaic Panels Array with Partial Shading Using the IPSM with Implementation Both in Simulation as in Hardware

Energies, 2020
This article presents a method for the Maximum Power Point Tracking (MPPT) of a Photovoltaic (PV) panels array with partial shading, applying an Improved Pattern Search Method (IPSM).
Andrés Tobón, Julián Peláez-Restrepo, Jhon Montano, Mariana Durango, Jorge Herrera, Asier Ibeas   +5 more
doaj   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

FLAGaTST: Fuzzy Logic Transformed Adversarial GAN and Time Series Transformer for Robust MPPT Under Partial Shading Conditions

IEEE Access
Partial shading poses a significant challenge in photovoltaic systems by creating multiple peaks in the power-voltage curve, complicating the task of accurately tracking the Maximum Power Point.
E. Elakkiya, S. Antony Raj, S. Priya
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Development of an MPPT-Based Genetic Algorithm for Photovoltaic Systems versus Classical MPPT Techniques in Scenarios with Partial Shading

Inventions
Photovoltaic (PV) systems face challenges in achieving maximum energy extraction due to the non-linear nature of their current versus voltage (IxV) characteristics, which are influenced by temperature and solar irradiation.
Fernando Marcos de Oliveira, Marcelo Henrique Manzke Brandt, Fabiano Salvadori, José Enrique Eirez Izquierdo, Marco Roberto Cavallari, Oswaldo Hideo Ando Junior   +5 more
doaj   +1 more source