Results 81 to 90 of about 1,668,359 (293)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Efficiency of Photovoltaic Systems in Mountainous Areas

, 2018
Photovoltaic (PV) systems have received much attention in recent years due to their ability of efficiently converting solar power into electricity, which offers important benefits to the environment.
Chitturi, Sri Rama Phanindra, Elmenreich, Wilfried, Sharma, Ekanki   +2 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

MPPT of a Photovoltaic Panels Array with Partial Shading Using the IPSM with Implementation Both in Simulation as in Hardware

Energies, 2020
This article presents a method for the Maximum Power Point Tracking (MPPT) of a Photovoltaic (PV) panels array with partial shading, applying an Improved Pattern Search Method (IPSM).
Andrés Tobón, Julián Peláez-Restrepo, Jhon Montano, Mariana Durango, Jorge Herrera, Asier Ibeas   +5 more
doaj   +1 more source

Power of unentangled measurements on two antiparallel spins

, 2007
We consider a pair of antiparallel spins polarized in a random direction to encode quantum information. We wish to extract as much information as possible on the polarization direction attainable by an unentangled measurement, i.e., by a measurement ...
A. Peres, C. W. Helstrom, E. B. Davies, P. W. Shor, T. Vértesi, W. Rudin   +5 more
core   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

FLAGaTST: Fuzzy Logic Transformed Adversarial GAN and Time Series Transformer for Robust MPPT Under Partial Shading Conditions

IEEE Access
Partial shading poses a significant challenge in photovoltaic systems by creating multiple peaks in the power-voltage curve, complicating the task of accurately tracking the Maximum Power Point.
E. Elakkiya, S. Antony Raj, S. Priya
doaj   +1 more source