Results 71 to 80 of about 7,989,093 (301)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
ArrayThe growing number of cyber threats and the increasing complexity of university distributed computing networks necessitate a multifactor approach to selecting an information security system (ISS).
Valery Lakhno +4 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A social licence to operate: Corporate social responsibility, local communities and the constitution of global production networks [PDF]
, 2015 This article contributes to the theorization of the role of informal regulation (undertaken by leading firms) in the ongoing organization of global production networks.
ROBYN MAYES, Mayes, Robyn
core +1 more source
BMC PsychologyBackground Gratitude interventions have shown various psychological benefits, including enhanced motivation in academic settings. However, their impact on work engagement - a key factor in employee well-being and organizational performance - remains ...
Noriko Yamagishi +2 more
doaj +1 more source
Intangibles, Global Networks & Corporate Social Responsibility
Symphonya, 2010 Network organisations emphasise the importance of corporate and product intangible assets. In global competition, the managerial economics of intangibles imposes new network policies of corporate social responsibility, dominated by global social issues ...
Silvio M. Brondoni
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Networks and Partnerships of Global Governance
Politikon, 2014 Recently, literature on the problem of legitimacy in/of global governance (GG) institutions, networks and/or partnerships has considerably increased.
Mohamed Hamchi, Samia Rebiai
doaj +1 more source