Results 121 to 130 of about 2,964,939 (305)

Offenheit als demokratisches Prinzip

Library Ideas, 2017
Nikolaus Hamann
doaj   +1 more source

Issues Related to Incorporating Northern Peatlands into Global Climate Models [PDF]

, 2009
Northern peatlands cover ~3–4 million km2 (~10% of the land north of 45°N) and contain ~200–400 Pg carbon (~10–20% of total global soil carbon), almost entirely as peat (organic soil).
Frolking, Steve, Lawrence, David, Roulet, Nigel T   +2 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Multiple Interfaces of Big Pharma and the Change of Global Health Governance in the Face of HIV/AIDS [PDF]

By using a game theoretical approach and the notion of “forum” or “regime shifting” this paper examines the multiple interfaces of the multinational pharmaceutical corporations (MNPCs) with their major counterparts at home and abroad, including the ...
Jan Peter Wogart
core  

PICES Press, Vol. 6, No. 2, July 1998 [PDF]

, 1998
CREAMS, PICES and the exploration of the Japan/East Sea The state of the eastern North Pacific from September 97 to February 98 The state of the western North Pacific in the second half of 1997 The status of the Bering Sea in the second half of ...

core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Evidences for a quasi 60-year North Atlantic Oscillation since 1700 and its meaning for global climate change

, 2012
The North Atlantic Oscillation (NAO) obtained using instrumental and documentary proxy predictors from Eurasia is found to be characterized by a quasi 60-year dominant oscillation since 1650.
A Bath, A Mazzarella, A Mazzarella, A Mazzarella, Adriano Mazzarella, B Komitov, BA Tinsley, C Loehle, CL Wolff, D Camuffo, DE Black, FR Stephenson, G North, H Gleisner, J Lean, J Luterbacher, J Luterbacher, JC Rogers, JW Hurrell, LB Klyashtorin, MB Enghoff, MF Knudsen, MG Ogurtsov, N Scafetta, NA Rayner, Nicola Scafetta, P Brohan, PD Jones, R Agnihotri, RT Patterson, S Jevrejeva, SM Silverman, V Trouet   +32 more
core   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source