Results 131 to 140 of about 9,446,042 (344)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Applying the Information–Motivation–Behavioral Skills model to a video-assisted HPV intervention to promote self-screening uptake: a qualitative study in Western Kenya

BMJ Global Health
Introduction Human papillomavirus (HPV) is the leading source of cervical cancer in Kenya. HPV, like other sexually transmitted infections, is stigmatised, which hinders efforts to address the disease.
Michelle Huang, Hanul Choi, Haley Dion, Laya Sathyan, Emily Herfel, Breandan Makhulo, Jeniffer Ambaka, Megan J. Huchko   +7 more
doaj   +1 more source

Intellectual Property Rights and South-North Global Innovation Networks [PDF]

This paper explores the role of IPR protection in the emergence of R&D linkages from newly emerging economies. Using data from a new survey on Chinese and Indian firms in the ICT sector, we find IPR protection to be key in the engagement of Southern ...
A. Naghavi, G. Prarolo, M. Comune
core  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Exploring the causal relationship between the antecedents and consequences of talent management for early career academics in South African higher education institutions

SA Journal of Human Resource Management, 2018
Orientation: South African public higher education institutions (HEIs) are facing significant challenges to attract and retain quality early career academics.
Dorcas L. Lesenyeho, Nicolene E. Barkhuizen, Nico E. Schutte   +2 more
doaj   +1 more source

Sustainable investment in Turkey: issue brief [PDF]

, 2011
IFC launched a series of sustainable investment country reports initially covering the largest emerging capital markets attracting global portfolio investors: Brazil, India, and China.
Ararat, Melsa, Suel, Esra, Yurtoğlu, Burçin B.   +2 more
core  

The Myth of Formality in the Global North: Informality‐as‐Innovation in Dutch Governance

International Journal of Urban and Regional Research, 2019
Why has urban informality in the global North received so little attention? We suggest that this neglect can be explained in part by the tendency of scholarship to reproduce the myth of Northern formality: the widely held belief that informality occurs ...
R. Jaffe, M. Koster
semanticscholar   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Issues Related to Incorporating Northern Peatlands into Global Climate Models [PDF]

, 2009
Northern peatlands cover ~3–4 million km2 (~10% of the land north of 45°N) and contain ~200–400 Pg carbon (~10–20% of total global soil carbon), almost entirely as peat (organic soil).
Frolking, Steve, Lawrence, David, Roulet, Nigel T   +2 more
core   +1 more source