Results 121 to 130 of about 9,535,029 (378)
The Ascendency of Numerical Methods in Lens Design
Journal of Imaging, 2018 Advancement in physics often results from analyzing numerical data and then creating a theoretical model that can explain and predict those data. In the field of lens design, the reverse is true: longstanding theoretical understanding is being overtaken ...
Donald C. Dilworth
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Two algorithms for global optimization
Mathematical and Computer Modelling, 1995 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
C. M. Keller, A. V. Cabot, B. G. Flury
openaire +3 more sources
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
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FEBS Open Bio, EarlyView.TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo +11 more
wiley +1 more source
Bayesian stopping rules for multistart global optimization methods [PDF]
, 1987 C. G. E. Boender, A. H. G. Rinnooy Kan
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Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
FEBS Open Bio, EarlyView.We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
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Fuzzy clustering method based on genetic algorithm in intrusion detection study
Tongxin xuebao, 2009 Regarding the problem that fuzzy c-means algorithm（FCM） was sensitive to the initial value and converging to the local infinitesimal point easily, applies genetic algorithm to optimization of the FCM algorithm.Firstly, the results of FCM will be sent to ...
HUANG Min-ming LIN Bo-gang
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Expected Improvement in Efficient Global Optimization Through Bootstrapped Kriging - Replaces CentER DP 2010-62 [PDF]
This article uses a sequentialized experimental design to select simulation input com- binations for global optimization, based on Kriging (also called Gaussian process or spatial correlation modeling); this Kriging is used to analyze the input/output ...
Beers, W.C.M. van +2 more
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FEBS Open Bio, EarlyView.Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová +11 more
wiley +1 more source