Results 101 to 110 of about 419,297 (312)
Scalarizing cost-effective multiobjective optimization algorithms made possible with kriging [PDF]
, 2007 The use of kriging in cost-effective single-objective optimization is well established, and a wide variety of different criteria now exist for selecting design vectors to evaluate in the search for the global minimum.
Jan Sykulski +4 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Unifying local–global type properties in vector optimization [PDF]
, 2018 It is well-known that all local minimum points of a semistrictly quasiconvex real-valued function are global minimum points. Also, any local maximum point of an explicitly quasiconvex real-valued function is a global minimum point, provided that it ...
Nicolae Popovici +3 more
core +1 more source
Calibration of the E3SM Land Model Using Surrogate‐Based Global Optimization
Journal of Advances in Modeling Earth Systems, 2018 Calibration of the Energy Exascale Earth System Model (E3SM), land model (ELMv0) is challenging because of its model complexity, strong model nonlinearity, and significant computational requirements. Therefore, only a limited number of simulations can be
Dan Lu +3 more
doaj +1 more source
FEBS Letters, EarlyView.The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
Hole Filling for View Synthesis Using Depth Guided Global Optimization
IEEE Access, 2018 View synthesis is an effective way to generate multi-view contents from a limited number of views, and can be utilized for 2-D-to-3-D video conversion, multi-view video compression, and virtual reality. In the view synthesis techniques, depth-image-based
Guibo Luo, Yuesheng Zhu
doaj +1 more source
Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach
FEBS Letters, EarlyView.The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring +3 more
wiley +1 more source
A multi-start opposition-based particle swarm optimization algorithm with adaptive velocity for bound constrained global optimization [PDF]
, 2013 In this paper we present a multi-start particle swarm optimization algorithm for the global optimization of a function subject to bound constraints. The procedure consists of three main steps.
KAUCIC, MASSIMILIANO
core +1 more source
An Improved Artificial Bee Colony Algorithm With Fitness-Based Information
IEEE Access, 2019 Artificial bee colony (ABC) algorithm is widely known for its distinguished exploration ability. However, its exploitation ability is relatively poor.
Wan-Li Xiang +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source