Results 91 to 100 of about 419,297 (312)
A Direct Search Algorithm for Global Optimization
Algorithms, 2016 A direct search algorithm is proposed for minimizing an arbitrary real valued function. The algorithm uses a new function transformation and three simplex-based operations.
Enrique Baeyens +2 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
FRACTOP: A Geometric Partitioning Metaheuristic for Global Optimization [PDF]
, 1999 We propose a new metaheuristic, FRACTOP, for global optimization. FRACTOP is based on the geometric partitioning of the feasible region so that search metaheuristics such as Simulated Annealing (SA), or Genetic Algorithms (GA) which are activated in ...
Özdamar, Linet +3 more
core
Global optimization of bounded factorable functions with discontinuities [PDF]
, 2016 A deterministic global optimization method is developed for a class of discontinuous functions. McCormick’s method to obtain relaxations of nonconvex functions is extended to discontinuous factorable functions by representing a discontinuity with a step ...
Barton, Paul I., Wechsung, Achim
core +1 more source
Numerical analysis of quantization-based optimization
ETRI JournalWe propose a number-theory-based quantized mathematical optimization scheme for various NP-hard and similar problems. Conventional global optimization schemes, such as simulated and quantum annealing, assume stochastic properties that require multiple ...
Jinwuk Seok, Chang Sik Cho
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
A Geometric Approach to Global Optimization
Journal of Global Optimization, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Nickel, Stefan, Schöbel, Anita
openaire +4 more sources
Recent advances in surrogate-based optimization [PDF]
, 2009 The evaluation of aerospace designs is synonymous with the use of long running computationally intensive simulations. This fuels the desire to harness the efficiency of surrogate-based methods in aerospace design optimization.
Alexander I.J. Forrester +3 more
core +1 more source
InformationThis paper proposes the Open Competency Optimization (OCO) approach, based on adaptive combinatorial operators, to solve the Dynamic Green Traveling Salesman Problem (DG-TSP), which extends the classical TSP by incorporating dynamic travel conditions ...
Rim Benjelloun +2 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source