Results 81 to 90 of about 6,941,251 (285)

Application of reduced-set pareto-lipschitzian optimization to truss optimization [PDF]

open access: yes, 2015
In this paper, a recently proposed global Lipschitz optimization algorithm Pareto-Lipschitzian Optimization with Reduced-set (PLOR) is further developed, investigated and applied to truss optimization problems.
Mockus, J   +4 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

A New Hybrid Classical-quantum Algorithm For Continuous Global Optimization Problems

open access: yes, 2015
Grover’s algorithm can be employed in global optimization methods providing, in some cases, a quadratic speedup over classical algorithms. This paper describes a new method for continuous global optimization problems that uses a classical algorithm for ...
Lavor C., Lara P.C.S., Portugal R.
core   +1 more source

Calibration of the E3SM Land Model Using Surrogate‐Based Global Optimization

open access: yesJournal of Advances in Modeling Earth Systems, 2018
Calibration of the Energy Exascale Earth System Model (E3SM), land model (ELMv0) is challenging because of its model complexity, strong model nonlinearity, and significant computational requirements. Therefore, only a limited number of simulations can be
Dan Lu   +3 more
doaj   +1 more source

A Geometric Approach to Global Optimization

open access: yesJournal of Global Optimization, 1999
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Nickel, Stefan, Schöbel, Anita
openaire   +4 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Hole Filling for View Synthesis Using Depth Guided Global Optimization

open access: yesIEEE Access, 2018
View synthesis is an effective way to generate multi-view contents from a limited number of views, and can be utilized for 2-D-to-3-D video conversion, multi-view video compression, and virtual reality. In the view synthesis techniques, depth-image-based
Guibo Luo, Yuesheng Zhu
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

An Improved Artificial Bee Colony Algorithm With Fitness-Based Information

open access: yesIEEE Access, 2019
Artificial bee colony (ABC) algorithm is widely known for its distinguished exploration ability. However, its exploitation ability is relatively poor.
Wan-Li Xiang   +4 more
doaj   +1 more source

Global Optimization of Robotic Grasps

open access: yesRobotics: Science and Systems VII, 2011
This paper presents a procedure to optimize the quality of robotic grasps for objects that need to be held and manipulated in a specific way, characterized by a number of tight contact constraints. The main difficulties of the problem include that the set of feasible grasps is a manifold implicitly defined by a system of non-linear equations, the high ...
Rosales Gallegos, Carlos   +2 more
openaire   +3 more sources

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