Results 61 to 70 of about 1,487,743 (283)

An Enhanced Tree-Seed Algorithm for Function Optimization and Production Optimization

Biomimetics
As the fields of engineering, energy, and geology become increasingly complex, decision makers face escalating challenges that require skilled solutions to meet practical production needs.
Qingan Zhou, Rong Dai, Guoxiao Zhou, Shenghui Ma, Shunshe Luo   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The q-gradient method for global optimization

, 2013
The q-gradient is an extension of the classical gradient vector based on the concept of Jackson's derivative. Here we introduce a preliminary version of the q-gradient method for unconstrained global optimization. The main idea behind our approach is the
Galski, Roberto L., Ramos, Fernando M., Soterroni, Aline C.   +2 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Adaptive Tasmanian Devil Optimizer for Global Optimization and Application in Wireless Sensor Network Deployment

IEEE Access
The Tasmanian Devil Optimization (TDO) algorithm, a recently popular metaheuristic algorithm, exhibits issues such as slow convergence, low precision, and susceptibility to getting stuck in local optima when applied to practical problems.
Wei Wang, Lixin Lyu
doaj   +1 more source

Thermodynamics of Global Optimization

Physical Review Letters, 1998
Theoretical design of global optimization algorithms can profitably utilize recent statistical mechanical treatments of potential energy surfaces (PES's). Here we analyze a particular method to explain its success in locating global minima on surfaces with a multiple-funnel structure, where trapping in local minima with different morphologies is ...
Doye, J, Wales, D
openaire   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

An improved chaotic firefly algorithm for global numerical optimization

International Journal of Computational Intelligence Systems, 2018
Firefly algorithm (FA) is a prominent metaheuristc technique. It has been widely studied and hence there are a lot of modified FA variants proposed to solve hard optimization problems from various areas.
Ivona Brajević, Predrag Stanimirović
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Fast Task Scheduling With Model Predictive Control Integrating a Priority-Based Heuristic

IEEE Access
This paper presents a scalable Model Predictive Control (MPC) algorithm for task scheduling and real time re-scheduling. The use case motivating the work is given by the problem of managing the integration activities involved in the final assembly of the
Francesco Liberati, Manuel Donsante, Chiara Maria Francesca Cirino, Andrea Tortorelli   +3 more
doaj   +1 more source