Results 41 to 50 of about 6,941,251 (285)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Global descent methods for unconstrained global optimization

open access: yes, 2010
Global descent method, Global optimization, Local search, Modified function approach, Non-convex optimization,
D. Li   +7 more
core   +1 more source

Replication Data for: eSLP optimization algorithm

open access: yes, 2023
m-files implementing the eSLP optimization algorithm for the three simulations (3.1. - 3.3.) described in the associated paper. File README.txt contains analytical directions regarding requirements, how to verify the results and videos generated by the ...
Optimization, eSLP
core   +1 more source

A Procedure of Global Optimization and its Application to Estimate Parameters in Interaction Spatial Models [PDF]

open access: yesInternational Journal for Simulation and Multidisciplinary Design Optimization, 2010
This work concerns the calibration of trip distribution models issued from Transportation Planning. The optimal estimators are the global minima of a non-convex function.
Bez Edson Tadeu   +2 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Experimental Study of Excessive Local Refinement Reduction Techniques for Global Optimization DIRECT-Type Algorithms

open access: yesMathematics, 2022
This article considers a box-constrained global optimization problem for Lipschitz continuous functions with an unknown Lipschitz constant. The well-known derivative-free global search algorithm DIRECT (DIvide RECTangle) is a promising approach for such ...
Linas Stripinis, Remigijus Paulavičius
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Family of Hybrid Stochastic Conjugate Gradient Algorithms for Local and Global Minimization Problems

open access: yesMathematics, 2022
This paper contains two main parts, Part I and Part II, which discuss the local and global minimization problems, respectively. In Part I, a fresh conjugate gradient (CG) technique is suggested and then combined with a line-search technique to obtain a ...
Khalid Abdulaziz Alnowibet   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Constrained Mixed-Variable Design Optimization Based on Particle Swarm Optimizer with a Diversity Classifier for Cyclically Neighboring Subpopulations

open access: yesMathematics, 2020
In this research, an easy-to-use particle swarm optimizer (PSO) for solving constrained engineering design problems involving mixed-integer-discrete-continuous (MIDC) variables that adopt two kinds of diversity-enhancing mechanisms to achieve superior ...
Tae-Hyoung Kim   +2 more
doaj   +1 more source

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