Results 41 to 50 of about 419,297 (312)

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Flux Weakening Strategy Optimization for Five-Phase PM Machine with Concentrated Windings [PDF]

, 2012
The paper applies an Efficient Global Optimization method (EGO) to improve the efficiency, in flux weakening region, of a given 5-phase Permanent Magnet (PM) machine. An optimal control for the four independent currents is thus defined.
JILIN, Gong, ASLAN, Bassel, SEMAIL, Eric, GILLON, Frédéric   +3 more
core  

Enhancing Pediatric Asthma Homecare Management: The Potential of Deep Learning Associated with Spirometry-Labelled Data

Applied Sciences
A critical factor contributing to the burden of childhood asthma is the lack of effective self-management in homecare settings. Artificial intelligence (AI) and lung sound monitoring could help address this gap. Yet, existing AI-driven auscultation tools
Heidi Cleverley-Leblanc, Johan N. Siebert, Jonathan Doenz, Mary-Anne Hartley, Alain Gervaix, Constance Barazzone-Argiroffo, Laurence Lacroix, Isabelle Ruchonnet-Metrailler   +7 more
doaj   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

Testing approaches for global optimization of space trajectories [PDF]

, 2008
In this paper the procedures to test global search algorithms applied to space trajectory design problems are discussed. Furthermore, a number of performance indexes that can be used to evaluate the effectiveness of the tested algorithms are presented.
Vasile, M., Vasile, Massimiliano, VASILE M, MINISCI E, Minisci, Edmondo, Minisci, E., Locatelli, Marco, Locatelli, M.   +7 more
core  

A hybrid method for solving multi-objective global optimization problems [PDF]

, 2007
Real optimization problems often involve not one, but multiple objectives, usually in conflict. In single-objective optimization there exists a global optimum, while in the multi-objective case no optimal solution is clearly defined but rather a set of ...
Gómez López, Julio, Gil Montoya, Consolación, Gil Montoya, María Dolores, Márquez, Antonio, Baños Navarro, Raúl   +4 more
core   +1 more source

MyThisYourThat for interpretable identification of systematic bias in federated learning for biomedical images

npj Digital Medicine
Distributed collaborative learning is a promising approach for building predictive models for privacy-sensitive biomedical images. Here, several data owners (clients) train a joint model without sharing their original data.
Klavdiia Naumova, Arnout Devos, Sai Praneeth Karimireddy, Martin Jaggi, Mary-Anne Hartley   +4 more
doaj   +1 more source

Machine Learning in Quasi-Newton Methods

Axioms
In this article, we consider the correction of metric matrices in quasi-Newton methods (QNM) from the perspective of machine learning theory. Based on training information for estimating the matrix of the second derivatives of a function, we formulate a ...
Vladimir Krutikov, Elena Tovbis, Predrag Stanimirović, Lev Kazakovtsev, Darjan Karabašević   +4 more
doaj   +1 more source

Childhood Acute Lymphoblastic Leukemia Survival in Western Kenya: Reduction in Early Deaths and Treatment Abandonment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An earlier study on children diagnosed with acute lymphoblastic leukemia (ALL) at Moi Teaching and Referral Hospital (MTRH) in Kenya reported a low event‐free survival (EFS), excess treatment abandonment, and high induction mortality.
Gilbert Olbara, George Bogonko, Festus Njuguna, Sandra Langat, Martha Kipngetich, Dennis Njenga, Gertjan Johannes Kaspers, Terry Allen Vik   +7 more
wiley   +1 more source

A Procedure of Global Optimization and its Application to Estimate Parameters in Interaction Spatial Models [PDF]

International Journal for Simulation and Multidisciplinary Design Optimization, 2010
This work concerns the calibration of trip distribution models issued from Transportation Planning. The optimal estimators are the global minima of a non-convex function.
Bez Edson Tadeu, Gonçalves Mirian Buss, Souza de Cursi José Eduardo   +2 more
doaj   +1 more source