Results 41 to 50 of about 7,447,344 (290)

Machine Learning in Quasi-Newton Methods

Axioms
In this article, we consider the correction of metric matrices in quasi-Newton methods (QNM) from the perspective of machine learning theory. Based on training information for estimating the matrix of the second derivatives of a function, we formulate a ...
Vladimir Krutikov, Elena Tovbis, Predrag Stanimirović, Lev Kazakovtsev, Darjan Karabašević   +4 more
doaj   +1 more source

A global optimization approach for the linear two-level program

, 1993
Linear two-level programming deals with optimization problems in which the constraint region is implicity determined by another optimization problem. Mathematical programs of this type arise in connection with policy problems to which the Stackelberg ...
Tuy, Hoang,, Migdalas, Athanasios,, Värbrand, Peter,   +2 more
core   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Continuous GRASP with a local active-set method for bound-constrained global optimization

, 2010
Global optimization, Stochastic methods, Active-set methods, Heuristic, CGRASP, GENCAN,
GOZZI, Erico M., BIRGIN, Ernesto G., RESENDE, Mauricio G. C., SILVA, Ricardo M. A.   +3 more
core   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source

A Procedure of Global Optimization and its Application to Estimate Parameters in Interaction Spatial Models [PDF]

International Journal for Simulation and Multidisciplinary Design Optimization, 2010
This work concerns the calibration of trip distribution models issued from Transportation Planning. The optimal estimators are the global minima of a non-convex function.
Bez Edson Tadeu, Gonçalves Mirian Buss, Souza de Cursi José Eduardo   +2 more
doaj   +1 more source

Subdomain separability in global optimization

Journal of Global Optimization, 2022
AbstractWe introduce a generalization of separability for global optimization, presented in the context of a simple branch and bound method. Our results apply to continuously differentiable objective functions implemented as computer programs. A significant search space reduction can be expected to yield an acceleration of any global optimization ...
Jens Deussen, Uwe Naumann
openaire   +5 more sources

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Experimental Study of Excessive Local Refinement Reduction Techniques for Global Optimization DIRECT-Type Algorithms

Mathematics, 2022
This article considers a box-constrained global optimization problem for Lipschitz continuous functions with an unknown Lipschitz constant. The well-known derivative-free global search algorithm DIRECT (DIvide RECTangle) is a promising approach for such ...
Linas Stripinis, Remigijus Paulavičius
doaj   +1 more source

Novelty search for global optimization

Applied Mathematics and Computation, 2019
Novelty search is a tool in evolutionary and swarm robotics for maintaining the diversity of population needed for continuous robotic operation. It enables nature-inspired algorithms to evaluate solutions on the basis of the distance to their k-nearest neighbors in the search space.
Iztok Fister 0001, Andrés Iglesias 0001, Akemi Gálvez, Javier Del Ser, Eneko Osaba, Iztok Fister Jr., Matjaz Perc, Mitja Slavinec   +7 more
openaire   +5 more sources