Results 31 to 40 of about 1,487,743 (283)

Strengthening Community Antimicrobial Stewardship in Africa: A Systematic Review of the Roles, Challenges, and Opportunities of Community Health and Animal Health Workers [version 1; peer review: 1 approved, 1 approved with reservations]

Wellcome Open Research
Antimicrobial resistance (AMR) remains a critical global health challenge, and is mainly due to inappropriate antimicrobial use in human and animal health sectors.
Dathan Byonanebye, Mackline Hope, Reuben Kiggundu, Fahad Lwaigale, Herman Mwanja, Andrew Kambugu, Conrad Tumwine, JP Waswa, Hannigton Katumba, Vivian Twemanye, Flavia Dhikusooka, Francis Kakooza   +11 more
doaj   +1 more source

Diffusions for Global Optimization

SIAM Journal on Control and Optimization, 1986
This paper describes a problem of finding a global minimum of a real- valued function defined on the unit hypercube in Euclidean n-space. The problem is changed to a stochastic differential equation by using the gradient of the above function as the drift term and a diffusion term which is interpreted as a constant times the square root of ...
Geman, Stuart, Hwang, Chii-Ruey
openaire   +2 more sources

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges, Kelly A. Duffy, Sara McDonough, Evelyn Kurpiewski, R. Jennifer Randall, Allison Barz Leahy, Haley M. Newman, Joyce P. Lee, Stephen P. Hunger, Anne F. Reilly, David T. Teachey, Susan R. Rheingold, Daniel J. Zheng   +12 more
wiley   +1 more source

Utility of syndromic surveillance for the surveillance of healthcare-associated infections in resource-limited settings: a narrative review

Frontiers in Microbiology
Globally, Healthcare-associated infections (HCAIs) pose a significant threat to patient safety and healthcare systems. In low- and middle-income countries (LMICs), the lack of adequate resources to manage HCAIs, as well as the weak healthcare system ...
Herman Mwanja, J. P. Waswa, Reuben Kiggundu, Hope Mackline, Daniel Bulwadda, Daniel Bulwadda, Dathan M. Byonanebye, Dathan M. Byonanebye, Dathan M. Byonanebye, Andrew Kambugu, Francis Kakooza, Francis Kakooza   +11 more
doaj   +1 more source

Advances in global optimization of high brightness beams [PDF]

, 2019
High brightness electron beams play an important role in accelerator-based applications such as driving X-ray free electron laser (FEL) radiation. In this paper, we report on advances in global beam dynamics optimization of an accelerator design using ...
Qiang, J
core  

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Enhancing Pediatric Asthma Homecare Management: The Potential of Deep Learning Associated with Spirometry-Labelled Data

Applied Sciences
A critical factor contributing to the burden of childhood asthma is the lack of effective self-management in homecare settings. Artificial intelligence (AI) and lung sound monitoring could help address this gap. Yet, existing AI-driven auscultation tools
Heidi Cleverley-Leblanc, Johan N. Siebert, Jonathan Doenz, Mary-Anne Hartley, Alain Gervaix, Constance Barazzone-Argiroffo, Laurence Lacroix, Isabelle Ruchonnet-Metrailler   +7 more
doaj   +1 more source

Nonlinear Regression Problem of Material Functions Identification for Porous Media Plastic Flow

Engineering Transactions, 2015
In the paper we present the identification problem arising in modelling the processes of nucleation and growth of voids in the elastic–plastic media. Identification is carried out on the basis of Fisher's data measured on the cylindrical steel specimens ...
Z. Nowak, A. Stachurski
doaj   +1 more source

Continuous extremal optimization for Lennard-Jones Clusters

, 2004
In this paper, we explore a general-purpose heuristic algorithm for finding high-quality solutions to continuous optimization problems. The method, called continuous extremal optimization(CEO), can be considered as an extension of extremal optimization ...
Bing-Hong Wang, D. E. Goldberg, E. H. L. Aarts, J. Holland, L. T. Wille, Long-Jiu Cheng, M. R. Garey, S. Boettcher, S. Boettcher, Tao Zhou, W. Banzhaf, Wen-Jie Bai   +11 more
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source