Results 121 to 130 of about 419,297 (312)

Optimization using surrogate models and partially converged computational fluid dynamics simulations [PDF]

, 2006
Efficient methods for global aerodynamic optimization using computational fluid dynamics simulations should aim to reduce both the time taken to evaluate design concepts and the number of evaluations needed for optimization.
Alexander I.J. Forrester, Andy J. Keane, Keane, A.J., Forrester, A.I.J., Bressloff, N.W., Neil W. Bressloff   +5 more
core   +1 more source

Analysis of DRM game control

Tongxin xuebao, 2012
To overcome the limitations of individual rationality,a game control model was proposed.The controller of game is global rational.To achieve global optimization,the controller chooses strategies according to the control goal,and the controlled chooses ...
Guo-jun MA, Qing-qi PEI, Xiao-hong JIANG
doaj  

Advances in Henry Gas Solubility Optimization: A Physics-Inspired Metaheuristic Algorithm With Its Variants and Applications

IEEE Access
The Henry Gas Solubility Optimization (HGSO) is a physics-based metaheuristic inspired by Henry’s law, which describes the solubility of the gas in a liquid under specific pressure conditions. Since its introduction by Hashim et al.
Mohammed A. El-Shorbagy, Anas Bouaouda, Hossam A. Nabwey, Laith Abualigah, Fatma A. Hashim   +4 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Supply Chain (SC) Network Optimization [PDF]

, 2019
Supply chain network design and optimization is one of the most important strategic decisions that an organization has to make. SC network design decisions are strategic-level SC decisions because they have long-lasting effect on the firms' supply chain ...
Canser Bilir, Bilir, Canser
core   +1 more source

Structures and Properties of MgTiH_n Clusters (n ≤ 20)

Hydrogen
Magnesium hydride solids doped with transition metals have received attention recently as prospective hydrogen storage materials for a green energy source and a hydrogen economy.
Camryn Newland, D. Balamurugan, Jonathan T. Lyon   +2 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Parallel triangulated partitioning for black box optimization [PDF]

, 2006
We propose a parallel triangulation based partitioning algorithm (TRIOPT) for solving low dimensional bound-constrained black box global optimization problems.
Wu, Yong, Ozdamar, Linet, Kumar, Arun
core   +1 more source

Improved Hybrid A* Algorithm Based on Lemming Optimization for Path Planning of Autonomous Vehicles

Applied Sciences
Path planning for autonomous vehicles is a core component of intelligent transportation systems, playing a key role in ensuring driving safety, improving driving efficiency, and optimizing the user experience.
Yong Chen, Yuan Liu, Wei Xu
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source