Results 31 to 40 of about 1,466,009 (282)

Diffusions for Global Optimization

SIAM Journal on Control and Optimization, 1986
This paper describes a problem of finding a global minimum of a real- valued function defined on the unit hypercube in Euclidean n-space. The problem is changed to a stochastic differential equation by using the gradient of the above function as the drift term and a diffusion term which is interpreted as a constant times the square root of ...
Geman, Stuart, Hwang, Chii-Ruey
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

An informational approach to the global optimization of expensive-to-evaluate functions

, 2007
In many global optimization problems motivated by engineering applications, the number of function evaluations is severely limited by time or cost. To ensure that each evaluation contributes to the localization of good candidates for the role of global ...
Département Signaux, Emmanuel Vazquez, Eric Walter, Julien Villemonteix, Renault S. A, Systèmes Électroniques   +5 more
core   +4 more sources

Utility of syndromic surveillance for the surveillance of healthcare-associated infections in resource-limited settings: a narrative review

Frontiers in Microbiology
Globally, Healthcare-associated infections (HCAIs) pose a significant threat to patient safety and healthcare systems. In low- and middle-income countries (LMICs), the lack of adequate resources to manage HCAIs, as well as the weak healthcare system ...
Herman Mwanja, J. P. Waswa, Reuben Kiggundu, Hope Mackline, Daniel Bulwadda, Daniel Bulwadda, Dathan M. Byonanebye, Dathan M. Byonanebye, Dathan M. Byonanebye, Andrew Kambugu, Francis Kakooza, Francis Kakooza   +11 more
doaj   +1 more source

Nonlinear Regression Problem of Material Functions Identification for Porous Media Plastic Flow

Engineering Transactions, 2015
In the paper we present the identification problem arising in modelling the processes of nucleation and growth of voids in the elastic–plastic media. Identification is carried out on the basis of Fisher's data measured on the cylindrical steel specimens ...
Z. Nowak, A. Stachurski
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Active Bayesian Optimization: Minimizing Minimizer Entropy [PDF]

, 2012
The ultimate goal of optimization is to find the minimizer of a target function.However, typical criteria for active optimization often ignore the uncertainty about the minimizer.
Nassar, Marcel, Park, Il Memming, Park, Mijung   +2 more
core  

The True Destination of EGO is Multi-local Optimization

, 2017
Efficient global optimization is a popular algorithm for the optimization of expensive multimodal black-box functions. One important reason for its popularity is its theoretical foundation of global convergence.
Preuss, Mike, Wessing, Simon
core   +1 more source

Enhancing Pediatric Asthma Homecare Management: The Potential of Deep Learning Associated with Spirometry-Labelled Data

Applied Sciences
A critical factor contributing to the burden of childhood asthma is the lack of effective self-management in homecare settings. Artificial intelligence (AI) and lung sound monitoring could help address this gap. Yet, existing AI-driven auscultation tools
Heidi Cleverley-Leblanc, Johan N. Siebert, Jonathan Doenz, Mary-Anne Hartley, Alain Gervaix, Constance Barazzone-Argiroffo, Laurence Lacroix, Isabelle Ruchonnet-Metrailler   +7 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source