Results 21 to 30 of about 427 (87)

Impact of osteitis and biofilm formation and correlation between both in diffuse sinonasal polyposis in

Alexandria Journal of Medicine, 2016
Background: The pathogenesis of diffuse sinonasal polyposis is still not completely established, possible explanations are osteitis, aeroallergens, fungal sinusitis and biofilms. There are no reports in Egypt about osteitis and biofilms in those patients.
Ayman Moustafa Al-Madani, Suzan Mohamed Helal, Hoda Mahmoud Khalifa, Moustafa Mohamed Abdelnaby   +3 more
doaj   +1 more source

Correlation of BMP2 with Degree of Osteitisin Primary CRS with and without nasal Polyps

Biology, Medicine & Natural Product Chemistry
Chronic rhinosinusitis (CRS) is an inflammation of the nasal mucosa and paranasal sinuses, persisting for over12 weeks. CRS involves a remodeling process and opacification known as osteitis, resulting from type 2 and non-type two inflammation.
Edi Handoko, David Santoso, Iriana Maharani, Yuyun Yueniwati P.W, Tanti Agustina   +4 more
doaj   +1 more source

Digital Learning Meets Diagnostic Dentistry: A Mixed‐Methods Study to Evaluate Intraoral Periapical Radiograph Interpretation

European Journal of Dental Education, EarlyView.
ABSTRACT Introduction Despite increased use of e‐learning, its value in developing practical diagnostic competencies, particularly in oral radiology, remains unclear. The purpose of this study was to evaluate changes in students' IOPAR interpretation scores and structured reporting after participation in an interactive, self‐directed e‐learning module.
Swarna Yerebairapura Math, Jia Yi Yong, Zee Hoe Teh, Preena Sidhu, Omer Sheriff Sultan, Mohd Fadzil Bin Zainal Anuar, Devarasa Murugeshappa, Camila Pacheco‐Pereira   +7 more
wiley   +1 more source

Thirty Years of Autologous Platelet Concentrates: From Platelet‐Rich Plasma to Platelet‐Rich Fibrin

Journal of Periodontal Research, EarlyView.
This review highlights the 30 years of evolution of APCs, with a focus on their clinical applications and recent technological advancements. ABSTRACT Nearly three decades have now passed since autologous platelet concentrates (APCs) were introduced into clinical practice.
Richard J. Miron, Nathan E. Estrin, Paras Ahmad, Nima Farshidfar, Masako Fujioka‐Kobayashi, Yufeng Zhang, Mario Romandini, Reinhard Gruber   +7 more
wiley   +1 more source

Apremilast in Japanese patients with palmoplantar pustulosis: A randomized, Phase 3 trial

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 6, Page 994-1004, June 2026.
In this Phase 3 trial of Japanese patients with moderate to severe PPP (NCT05174065), significantly more patients achieved PPPASI‐50 at Week 16 with apremilast versus placebo. Patient‐reported outcomes, including pruritus and pain/discomfort, also showed significantly greater decreases at Week 16 with apremilast versus placebo.
Tadashi Terui, Yukari Okubo, Satomi Kobayashi, Akimichi Morita, Shinichi Imafuku, Yayoi Tada, Masatoshi Abe, Bruce Strober, Melinda Gooderham, Wendy Zhang, Junichiro Shimauchi, Masafumi Yaguchi, Takeshi Kimura, Ryuichi Ogawa, Hamid Amouzadeh, Masamoto Murakami   +15 more
wiley   +1 more source

Efficacy and safety of brodalumab in palmoplantar pustulosis: A 68‐week randomized Phase 3 trial

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 887-899, May 2026.
This open‐label study is a continuation of the 16‐week double‐blind, Phase 3 trial assessing the efficacy and safety of brodalumab 210 mg subcutaneously, till a 68‐week extension period. Continued improvement was seen in the PPPASI 50/75/90 responses, PPPSI scores, PGA 0/1 responses and DLQI. Abstract Background The efficacy and safety of brodalumab in
Masamoto Murakami, Yukari Okubo, Satomi Kobayashi, Natsuko Kikuta, Yoshiumi Ouchi, Kenta Shishido, Tadashi Terui   +6 more
wiley   +1 more source

Janus Kinase Inhibitors for Treatment of Palmoplantar Pustulosis, Generalized Pustular Psoriasis, and Palmoplantar Pustular Psoriasis: A Systematic Review of the Literature

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Introduction Palmoplantar pustulosis (PPP) is a chronic, recurrent, inflammatory disease and assumed to be a subtype of psoriasis. Pustular psoriasis (PP) is a chronic inflammatory disease that is further subclassified into various entities with different presentations including generalized pustular psoriasis (GPP) and palmoplantar pustular ...
Mahshid Sadat Ansari, Sama Heidari, Elnaz Pourgholi, Saeed Bahramian, Nasim Tootoonchi, Seyed Mohammad Vahabi   +5 more
wiley   +1 more source

Palmoplantar pustulosis: pathogenesis, differential diagnosis, and treatment

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 4, Page 516-535, April 2026.
Summary Palmoplantar pustulosis (PPP) is a chronic inflammatory and often painful disease characterized by sterile pustules on the palms and soles, significantly impairing quality of life. Women are more frequently affected than men, and smoking is a major trigger. Under biologic therapies, especially TNF antagonists, a paradoxical PPP may occur.
Rotraut Mössner, Tanja Fetter, Robert Sabat, Ulrich Mrowietz, Neda Cramer, Dagmar Wilsmann‐Theis   +5 more
wiley   +1 more source

Beyond Isotretinoin: A Narrative Review of Emerging Systemic Therapies for Moderate‐to‐Severe Acne

Journal of Cosmetic Dermatology, Volume 25, Issue 4, April 2026.
ABSTRACT Background Acne vulgaris is a common inflammatory skin disorder with significant psychosocial impact. While isotretinoin remains the gold standard for moderate‐to‐severe cases, its adverse effects and teratogenicity underscore the need for alternative systemic therapies.
Nello Tommasino, Maria Carmela Annunziata, Luca Potestio, Maddalena Napolitano   +3 more
wiley   +1 more source

Intent to Treat Analysis of the Primary and Secondary Outcomes for the ODINN Intact Fish Skin Graft for Deep Diabetic Foot Wounds Trial

International Wound Journal, Volume 23, Issue 3, March 2026.
ABSTRACT There is a significant need for trials that evaluate the treatment of University of Texas (UT) grade 2 and 3 diabetic foot ulcers (bone, joint, or tendon exposed wounds). We undertook a trial looking at the effect of intact fish skin graft (IFSG) on these deep and difficult‐to‐heal ulcers.
Dured Dardari, Alberto Piaggesi, Louis Potier, Ariane Sultan, Holger Diener, Maud Francois, Bernhard Dorweiler, Benjamin Bouillet, Jocelyne M'Bemba, Lucy Chaillous, Giacomo Clerici, Laurence Kessler, Walter Wetzel‐Roth, Martin Storck, Dereck Shi, Olafur Davidsson, Baldur Baldursson, Hilmar Kjartansson, Guillaume Charpentier, John C. Lantis II   +19 more
wiley   +1 more source