Results 31 to 40 of about 1,022 (137)

Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (Review) [PDF]

, 2013
Diabetes mellitus is a common condition that leads to high blood glucose concentrations, with around 2.8 million people affected in the UK (approximately 4.3% of the population). Some people with diabetes can develop ulcers on their feet.
Cullum, Nicky, Dumville, Jo C., Game, Fran, Hinchliffe, Robert J., Peinemann, Frank, Stubbs, Nikki, Sweeting, Michael   +6 more
core   +1 more source

Apremilast in Japanese patients with palmoplantar pustulosis: A randomized, Phase 3 trial

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In this Phase 3 trial of Japanese patients with moderate to severe PPP (NCT05174065), significantly more patients achieved PPPASI‐50 at Week 16 with apremilast versus placebo. Patient‐reported outcomes, including pruritus and pain/discomfort, also showed significantly greater decreases at Week 16 with apremilast versus placebo.
Tadashi Terui, Yukari Okubo, Satomi Kobayashi, Akimichi Morita, Shinichi Imafuku, Yayoi Tada, Masatoshi Abe, Bruce Strober, Melinda Gooderham, Wendy Zhang, Junichiro Shimauchi, Masafumi Yaguchi, Takeshi Kimura, Ryuichi Ogawa, Hamid Amouzadeh, Masamoto Murakami   +15 more
wiley   +1 more source

Monitoring cartilage loss in the hands and wrists in rheumatoid arthritis with magnetic resonance imaging in a multi-center clinical trial: IMPRESS (NCT00425932) [PDF]

, 2013
INTRODUCTION: Magnetic resonance imaging (MRI) is increasingly being used in clinical trials of rheumatoid arthritis (RA) because of its superiority over x-ray radiography (XR) in detecting and monitoring change in bone erosion, osteitis and synovitis ...
Charles G Peterfy, Ewa Olech, Joan T Merrill, Julie C DiCarlo, Norman B Gaylis, Peter J Countryman   +5 more
core   +1 more source

Thirty Years of Autologous Platelet Concentrates: From Platelet‐Rich Plasma to Platelet‐Rich Fibrin

Journal of Periodontal Research, EarlyView.
This review highlights the 30 years of evolution of APCs, with a focus on their clinical applications and recent technological advancements. ABSTRACT Nearly three decades have now passed since autologous platelet concentrates (APCs) were introduced into clinical practice.
Richard J. Miron, Nathan E. Estrin, Paras Ahmad, Nima Farshidfar, Masako Fujioka‐Kobayashi, Yufeng Zhang, Mario Romandini, Reinhard Gruber   +7 more
wiley   +1 more source

Recalcitrant chronic rhinosinusitis. Difficulties in diagnosis and treatment [PDF]

, 2011
Chronische rhinosinusitis wordt gekenmerkt door blokkade van de neus of nasale invloed, gecombineerd met aangezichtspijn en/of reukverlies gedurende meer dan 12 weken.
Videler, W.J.M.
core   +2 more sources

A Review of Ankylosing Spondylitis [PDF]

, 2017
Ankylosing spondylitis (AS) is a systemic autoimmune disorder that induces ankylosis of the spine (fusion of the vertebrae at their various joints) and inflammatory arthritis of peripheral joints among other symptoms.
Owen, Hannah L
core   +1 more source

Efficacy and safety of brodalumab in palmoplantar pustulosis: A 68‐week randomized Phase 3 trial

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 887-899, May 2026.
This open‐label study is a continuation of the 16‐week double‐blind, Phase 3 trial assessing the efficacy and safety of brodalumab 210 mg subcutaneously, till a 68‐week extension period. Continued improvement was seen in the PPPASI 50/75/90 responses, PPPSI scores, PGA 0/1 responses and DLQI. Abstract Background The efficacy and safety of brodalumab in
Masamoto Murakami, Yukari Okubo, Satomi Kobayashi, Natsuko Kikuta, Yoshiumi Ouchi, Kenta Shishido, Tadashi Terui   +6 more
wiley   +1 more source

Janus Kinase Inhibitors for Treatment of Palmoplantar Pustulosis, Generalized Pustular Psoriasis, and Palmoplantar Pustular Psoriasis: A Systematic Review of the Literature

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Introduction Palmoplantar pustulosis (PPP) is a chronic, recurrent, inflammatory disease and assumed to be a subtype of psoriasis. Pustular psoriasis (PP) is a chronic inflammatory disease that is further subclassified into various entities with different presentations including generalized pustular psoriasis (GPP) and palmoplantar pustular ...
Mahshid Sadat Ansari, Sama Heidari, Elnaz Pourgholi, Saeed Bahramian, Nasim Tootoonchi, Seyed Mohammad Vahabi   +5 more
wiley   +1 more source

Palmoplantar pustulosis: pathogenesis, differential diagnosis, and treatment

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 4, Page 516-535, April 2026.
Summary Palmoplantar pustulosis (PPP) is a chronic inflammatory and often painful disease characterized by sterile pustules on the palms and soles, significantly impairing quality of life. Women are more frequently affected than men, and smoking is a major trigger. Under biologic therapies, especially TNF antagonists, a paradoxical PPP may occur.
Rotraut Mössner, Tanja Fetter, Robert Sabat, Ulrich Mrowietz, Neda Cramer, Dagmar Wilsmann‐Theis   +5 more
wiley   +1 more source

Beyond Isotretinoin: A Narrative Review of Emerging Systemic Therapies for Moderate‐to‐Severe Acne

Journal of Cosmetic Dermatology, Volume 25, Issue 4, April 2026.
ABSTRACT Background Acne vulgaris is a common inflammatory skin disorder with significant psychosocial impact. While isotretinoin remains the gold standard for moderate‐to‐severe cases, its adverse effects and teratogenicity underscore the need for alternative systemic therapies.
Nello Tommasino, Maria Carmela Annunziata, Luca Potestio, Maddalena Napolitano   +3 more
wiley   +1 more source