Results 111 to 120 of about 25,089,563 (315)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Global positioning system variables used to quantify external workload.
Global positioning system variables used to quantify external workload.
Simon Boisbluche (18275266) +7 more
core +1 more source
The Global Positioning System [PDF]
, 2005 The Global Positioning System (GPS) is quickly becoming part of the fabric of everyday life. Beyond recreational activities such as boating and backpacking, GPS receivers are becoming a very important tool to such industries as agriculture ...
Koostra, Benjamin K. +2 more
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Guidodontics: A global positioning system (GPS) to surgical Endodontics - A case series. [PDF]
J Conserv Dent, 2023 Sudha A, Krishnan A, Samant PS, Dubey S.
europepmc +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
SensorsHorizontal force–velocity profiling (FV) has become a prominent approach to evaluate sprinting performance and force/power characteristics in athletes. As optical timing gates (TGs) are the most prevalent and accessible athlete sprint testing measurement
Ming-Chang Tsai +5 more
doaj +1 more source
Jurnal Jaringan Telekomunikasi, 2023 The service queue system at motor vehicle repair shops in Malang city is still manual, customers must find the nearest repair shop and visit the repair shop then queue for service without knowing the queue information. With a system like that, it will be
Muhammad Abror +2 more
doaj