Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Global Positioning System-Derived Metrics and Machine Learning Models for Injury Prediction in Professional Rugby Union Players. [PDF]
Ren X +7 more
europepmc +1 more source
A Novel Approach to Global Positioning System Accuracy Assessment, Verified on LiDAR Alignment of One Million Kilometers at a Continent Scale, as a Foundation for Autonomous DRIVING Safety Analysis. [PDF]
Bedkowski J +10 more
europepmc +1 more source
Global Positioning System: Understanding Long Noncoding RNAs through Subcellular Localization [PDF]
Joana Carlevaro-Fita, Rory Johnson
openalex +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Position-specific workload and performance analysis in professional rugby union: Insights from global positioning system data and principal component analysis. [PDF]
Ren X +6 more
europepmc +1 more source
Acute and Chronic Workload Ratios of Perceived Exertion, Global Positioning System, and Running-Based Variables Between Starters and Non-starters: A Male Professional Team Study. [PDF]
Nobari H +3 more
europepmc +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
A Study on Bellman Ford Algorithm for Shortest Path Detection in Global Positioning System
Avinish Rai
openalex +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source

