Results 61 to 70 of about 51,349 (299)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
A Comprehensive Machine Learning Study to Classify Precipitation Type over Land from Global Precipitation Measurement Microwave Imager (GPM-GMI) Measurements [PDF]
, 2022 Precipitation type is a key parameter used for better retrieval of precipitation characteristics as well as to understand the cloud–convection–precipitation coupling processes.
Dong L. Wu +9 more
core +1 more source
Precipitation Microphysics of Tropical Cyclones over Northeast China in 2020
Remote Sensing, 2022 Landfalling tropical cyclones (TCs) in Northeast China are rare because of the region’s high latitude (>40°N). In 2020, Northeast China was affected by three TCs within half a month—the first time on record.
Aoqi Zhang +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Global Precipitation Measurement (GPM) Mission Development Status [PDF]
, 2011 Mission Objective: (1) Improve scientific understanding of the global water cycle and fresh water availability (2) Improve the accuracy of precipitation forecasts (3) Provide frequent and complete sampling of the Earth s precipitation Mission Description
Azarbarzin, Ardeshir Art
core +1 more source
Bulletin of the American Meteorological Society, 2015 Abstract As a component of Earth’s hydrologic cycle, and especially at higher latitudes, falling snow creates snowpack accumulation that in turn provides a large proportion of the freshwater resources required by many communities throughout the world.
Kimberly A. Reed +16 more
openaire +3 more sources
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
World Tour for Global Precipitation Measurement Movie [PDF]
, 2003 This visualization was created for the second of three featurettes for the Global Precipitation Measurement (GPM) project. The featurette was called Water for Tea.
Stuart Snodgrass, Joycelyn Thomson
core
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source