Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Espresso: A Global Deep Learning Model to Estimate Precipitation from Satellite Observations
Estimating precipitation is of critical importance to climate systems and decision-making processes. This paper presents Espresso, a deep learning model designed for estimating precipitation from satellite observations on a global scale.
Léa Berthomier, Laurent Perier
doaj +1 more source
Global-scale modeling of groundwater recharge [PDF]
Long-term average groundwater recharge, which is equivalent to renewable groundwater resources, is the major limiting factor for the sustainable use of groundwater.
P. Döll +5 more
core +2 more sources
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
The important of Global Precipitation Measurement in ungauged catchment
In line with the technological development in the remote sensing field like satellite data, the measurement of rainfall can be carried out by rainfall monitoring in large areas even in places that cannot be reached by conventional tools. This superiority can be utilized to get the rainfall in a region for the importance of water resources management ...
openaire +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
The driving mechanisms of particle precipitation during the moderate geomagnetic storm of 7 January 2005 [PDF]
International audienceThe arrival of an interplanetary coronal mass ejection (ICME) triggered a sudden storm commencement (SSC) at ~09:22 UT on the 7 January 2005. The ICME followed a quiet period in the solar wind and interplanetary magnetic field (IMF).
N. Longden +7 more
core +2 more sources
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Precipitation averaged across Europe, GPCC, 1914-1920 C.E.
DATA DESCRIPTION: Precipitation averaged across Europe, GPCC, 1914-1920 Citation: Alexander F. More, Christopher P. Loveluck, Heather Clifford, Michael J. Handley, Elena V. Korotkikh, Andrei V. Kurbatov, Michael McCormick and Paul A. Mayewski. (2020).
Global Precipitation Climatology Centre
core +1 more source
Robust assessment of future changes in extreme precipitation over the Rhine basin using a GCM [PDF]
Estimates of future changes in extremes of multiday precipitation sums are critical for estimates of future discharge extremes of large river basins. Here we use a large ensemble of global climate model SRES A1b scenario simulations to estimate changes ...
S. F. Kew +7 more
core +2 more sources

