Results 121 to 130 of about 1,312,704 (343)

The complex interaction between Global Production Networks, Digital Information Systems and International Knowledge Transfers [PDF]

open access: yes
Traditionally many studies of knowledge in economics have focused on localized networks and intra-regional collaborations. However, the rising frequency by which firms collaborate within the context of global networks of production and innovation, the ...
Dieter Ernst   +2 more
core  

The invisible networks of global production:Re-imagining the global value chain in legal research

open access: yes, 2020
Reviewing the burgeoning legal scholarship on global value chains to delineate the legal image of the global value chain and then comparing this legal image with images on global production in neighbouring social sciences research, in particular the ...
Beckers, Anna, Beckers, Anna; id_orcid
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Production Networks and Trade Patterns in East Asia: Regionalization or Globalization? [PDF]

open access: yes
This paper examines the implications of global production sharing for economic integration in East Asia, with emphasis on the behavior of trade flows in the wake of the 2008 global economic crisis.
Athukorala, Prema-chandra
core  

Local-global geographies of tacit knowledge production in London and New York's advertising and law professional service firms [PDF]

open access: yes, 2005
For economic geographers interest in the role of knowledge in economic activities and a ‘knowledge economy’ raises questions about how geography enables (and disables) learning and whether the production of tacit knowledge has exclusively local or ...
Faulconbridge, James R
core  

Is China decoupling from the global value chain? A quantitative analysis framework based on the global production network

open access: yesHumanities & Social Sciences Communications
In recent years, frequent global emergencies have disrupted international stability and prompted countries to decouple from Global Value Chain (GVC), raising critical questions about how to restore and manage the extent of such decoupling to mitigate ...
Chuke Jiang, Lizhi Xing
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Implications of social responsibility disclosure on global production network

open access: yes, 2013
This paper aims to discuss effectiveness of social responsibility disclosure in promoting global production network. Through a critical review on the theoretical development from supply chain to global production network, the global supply chain ...
Jin Jun Bo   +5 more
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

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