Results 131 to 140 of about 1,342,058 (331)
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Genomics knowledge and equity: a global public goods perspective of the patent system
Bulletin of the World Health Organization, 2004 Genomics, the comprehensive examination of an organism's entire set of genes and their interactions, will have a major impact on the way disease is diagnosed, prevented and treated in the new millennium.
Smith Richard D. +4 more
doaj
How can donors help build global public goods in health ? [PDF]
Aid to developing countries has largely neglected the population-wide health services that are core to communicable disease control in the developed world.
Das Gupta, Monica, Gostin, Lawrence
core
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Regional vs. Global Public Goods: The Case of Post-Communist Transition [PDF]
The paper discusses the role of regional public goods vs. global goods in influencing postcommunist transition in Central and Eastern Europe and former USSR with special attention given to three particular factors: (i) external anchoring of national ...
Artur Radziwill, Marek Dabrowski
core +3 more sources
Private versus public consumption within groups : testing the nature of goods from aggregate data [PDF]
We study the testability implications of public versus private consumption. The distinguishing feature of our approach is that we start from a revealed preference characterization of collectively rational behavior.
Bram De Rock +2 more
core
Der Klimagipfel in Durban: Ein Pyrrhussieg für das UN-Klimaregime? [PDF]
, 2012 Die Ergebnisse des Klimagipfels in Durban reproduzierten nur die strukturellen Widersprüche von Global Governance. Ohne grundlegende Reform des UN-Systems und der Anerkennung des Global Public Goods-Ansatzes bleiben die Klimaverhandlungen wirkungslose ...
Obrovsky, Michael
core
Aging and Cancer, EarlyView.This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst +4 more
wiley +1 more source
Imbalance of World Heritage List: did the UNESCO strategy work? [PDF]
The official intention of the UNESCO World Heritage List is to protect the global heritage. However, the imbalance of the distribution of Sites according to countries and continents is striking.
Bruno S. Frey, Lasse Steiner
core
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source