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The United Nations and Global Public Goods: Historical Contributions and Future Challenges.

Revue Internationale de Politique de Développement, 2012
Published by Palgrave MacmillanThis chapter explores the thesis that the United Nations’ (UN) most important contribution to the production of global public goods has been its role in creating the space and capacity to generate shared values.
Bruce Jenks
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Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Governing as commons or as global public goods: Two tales of power

International Journal of the Commons, 2019
Commons and global public goods have become popular concepts in academic debates on governance. Moreover, these concepts are no longer the exclusive domain of economists.
Nicolás Brando, Christiaan Boonen, Samuel Cogolati, Rutger Hagen, Nils Vanstappen, Jan Wouters   +5 more
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The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

The Internet as a global public good and the role of governments and multilateral organizations in global internet governance

Meridiano 47, 2018
The Internet presents social and economic attributes of a global public good, requiring governments and multilateral organizations to play central roles in Internet governance.
Mario Rodrigo Canazza
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Globalization and Global Public Goods [PDF]

, 2011
Everyday, the importance of global public goods (GPGs) is increasing in the globalization process. GPGs are public goods with benefits or costs (peace, crime, terrorism, disease etc.) that extend across countries and regions, across rich and poor population groups, and even across generations.
openaire   +3 more sources

What kind of goods are plant genetic resources for food and agriculture? Towards the identification and development of a new global commons

International Journal of the Commons, 2013
Plant genetic resources for food and agriculture (PGRFA) were once widely considered to be global public goods. Recently, however, access to subsets of PGRFA has been subject to various forms of exclusive technological and legal restrictions. In reaction,
Michael Halewood
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Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Genetically modified foods as global public goods

Suma de Negocios, 2014
"Genetically modified (GM) food has become very important in the field of research, as a result of its expansion in recent decades. As the right to food is a human right, it cannot be left in the hands of private sector developments exclusively, due to ...
Susana Herrero Olarte
doaj