Results 91 to 100 of about 26,756,386 (303)
Global Health Is (Local) Public Health [PDF]
North Carolina Medical Journal, 2010 Margaret E, Bentley, Gretchen, Van Vliet
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Global Public Health Informatics Program (GPHIP) [PDF]
In today\ue2\u20ac\u2122s world where diseases spread rapidly without respect for borders, officials rely on technology to deliver accurate information in real time.
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Challenges Confronting Global Public Health
Journal of Moral Theology, 2021 Among the challenges confronting global public health the author focuses, first, on pandemics and, to propose a solution, he discusses the Global Health Security Agenda platform that allows the international community to collaborate and prevent, detect ...
Keith Martin
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Division of Global Health Protection : extending the possibilities of public health globally [PDF]
No matter what the cause, the Division of Global Health Protection (DGHP) and its partners across CDC and the globe are working to protect health and save lives. Our programs have resources supporting 72 countries, with partnerships and technical support
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The global reach of public health [PDF]
Journal of Public Health, 2016 Ted, Schrecker, Eugene, Milne
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Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
PLOS Global Public Health[This corrects the article DOI: 10.1371/journal.pgph.0001880.].
PLOS Global Public Health Staff
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Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source