Results 161 to 170 of about 112,742 (254)

Multiscale Spatial Fusion Feature‐Driven Characterization of Gastric Cancer Invasive Margins: A Multicenter Cohort Study for Preoperative Accurate Differentiation Between T4a and T4b Subtypes

Advanced Science, EarlyView.
This study develops a multi‐dimensional vision Transformer‐based model, GAVR, to accurately distinguish gastric cancer T4a/b stages preoperatively. Validated across multi‐center cohorts, it achieves excellent performance and significantly improves radiologists’ diagnostic accuracy, offering a promising tool for clinical decision‐making.
Guoliang Zheng, Xiaomiao Chai, Peng Jin, Xin Xin, Yingjie Li, Chun Yang, Jia Wei, Zishuo Yan, Jingyu Zhang, Qianning Zhao, Yingchen Han, Ning Zhang, Fuze Li, Bo Qiao, Huan Wang, Huachuan Zheng, Yan Li, Xin Zhang, Yan Zhao, Wenjun Mao, Jing Zhang   +20 more
wiley   +1 more source

Highlights from the first interdisciplinary summit of the European Association of Cardiovascular Imaging and the European Society for Cardiovascular Radiology. [PDF]

Eur Heart J Cardiovasc Imaging
Vliegenthart R, Baritussio A, Budde RPJ, Pontone G, van Assen M, Dacher JN, Danad I, Delgado V, Delgado V, Dweck MR, van der Harst P, Hirsch A, Huisman M, Kozerke S, Pezel T, Pugliese F, Westwood M, Williams MC, Paar MH, Manka R, Salgado R, Nijveldt R.   +21 more
europepmc   +1 more source

From Chatbots to Co‐Scientists: The Impact of Knowledge‐Generating AI (AI 4.0) on Healthcare and Research

Advanced Science, EarlyView.
This perspective contrasts the historical, linear progression of early AI with the dynamic, iterative nature of AI 4.0; and it describes the real‐world medical applications and the necessary evolution of laboratory infrastructure brought about by AI 4.0.
Weida Liu, Gary Peltz
wiley   +1 more source

Radiology's Triple Helix: Value, Patient Care, and the Planet. [PDF]

J Am Coll Radiol
Doo FX.
europepmc   +1 more source

Systemic Nanomechanical Single‐Cell Profiling Reveals Mechanophenotype Transitions Under Therapeutic Perturbation

Advanced Science, EarlyView.
Single‐cell mechanomics demonstrates that pharmacological perturbation changes cytoskeletal and cortical structure, suppressing cancer cell invasiveness. By integrating atomic force microscopy (AFM)‐based cortical measurements with stimulated emission depletion (STED)‐resolved adhesion and cytoskeletal organization, this approach identifies nanoscale ...
Minhee Ku, Jinwon Kwon, Nara Yoon, Hyung Kwon Byeon, Jaemoon Yang   +4 more
wiley   +1 more source

Associations among structural brain alterations, respiratory symptoms and cognitive impairment in patients with chronic obstructive pulmonary disease-related subclinical cognitive vulnerability: a multimodal neuroimaging study. [PDF]

Front Aging Neurosci
Wang C, Lin S, Zhao K, Zhan Y, Qiu Y, Peng K, Wang X, Lui S, Liu Y, Qiu S.   +9 more
europepmc   +1 more source

A Programmable Calcification Nanoplatform for Loco‐Regional Calcification‐Immune Hepatocellular Carcinoma Therapy

Advanced Science, EarlyView.
An in situ‐grown BP‐CaO2 nanoplatform supplies coordinated Ca2+, endogenous phosphate, and oxidative stress to convert tumor calcification from a passive endpoint into an active immune‐remodeling process. Widespread hydroxyapatite deposition is visualized by CT, while multi‐omics reveals MCOLN2 as a calcium‐responsive mediator linking biomineralization
Long Liu, Peng Li, Zhixiang Lu, Shuqin Xu, Juanjuan Wang, Kai Ma, Haodong Yu, Can Zhou, Hu Chen, Gang Liu, Yi Lyu, Shuang Bai   +11 more
wiley   +1 more source

Prevalence and Correlates of Steatotic Liver Disease Among People With HIV in Uganda. [PDF]

Open Forum Infect Dis
Bibangambah P, Acan M, Ghoshhajra B, Erem G, Nassanga R, Ochieng A, Thondapu V, Lu MT, Randhawa M, Takigami A, Reynolds Z, Atwiine F, Tindimwebwa E, Gilbert RF, Hoepner SS, Passell E, Sagar S, Tong Y, Ntusi NAB, Hahn J, Gaziano T, Longenecker CT, Tsai AC, Manne-Goehler JM, Asiimwe S, Okello S, Siedner MJ.   +26 more
europepmc   +1 more source

Spatiotemporally Ultrasound‐Controlled Nanoparticles Reprogramming Immunostimulatory Antigen‐Presenting Cancer‐Associated Fibroblasts to Enhance Cancer Immunotherapy

Advanced Science, EarlyView.
We developed an ultrasound‐controlled biomimetic nanoplatform, mRNA/V@M NPs, to co‐deliver CD74 mRNA and V‐9302 for fibrotic TNBC therapy. CD74 mRNA reprograms myCAFs into antigen‐presenting apCAF cells through the CD74‐MHC II pathway, while V‐9302 induces ICD and activates MHC I‐CD8+ T cell immunity.
Chen Ai, Weikai Sun, Yuxuan Zhao, Daqian Sun, Ting Meng, Yafei Qi, Fengyang Jiang, Jintang Sun, Zhiliang Gao, Dexin Yu   +9 more
wiley   +1 more source

Detecting early structural and functional myocardial alterations in patients with repaired tetralogy of fallot: a prospective MRI study. [PDF]

Sci Rep
Kappler HE, Kocher N, Berg S, Uhl M, Menza M, Jung B, Schlett CL, Zürn C, Stiller B, Wintergerst C, Taron J.   +10 more
europepmc   +1 more source