Results 121 to 130 of about 97,876 (260)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Study protocol for OtoSurg 1: A prospective evaluation of worldwide tonsillectomy indications, techniques, and outcomes. [PDF]

PLoS One
Elwell Z, Finnegan E, Motwani K, Hwang J, Washington C, Johnson KG, Su AY, Patterson RH, Qian ZJ, Shaw CA, Din T, Kligerman MP, Global Otolaryngology-Head and Neck Surgery Initiative.   +12 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Towards a common core dataset for critical care: a registry-centered vision for global improvement. [PDF]

Crit Care Sci
Pari V, Pilcher D, Pisani L.
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Policy monitoring indexes targeting non-communicable diseases: protocol for a scoping review. [PDF]

BMJ Open
Bjørnarå HB, Flodgren GM, Helleve A.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

COVID-19 in Ghana-Using the health system framework to describe RISE-mitigation strategies for COVID-19 response and recovery in Ghana. [PDF]

Front Public Health
Forson PK, Ahiataku DE, Owusu R, Andrew Musah MA, Mustapha A, Adesons S, Eyeson JA, Wuddah-Martey A, Nimako BA, Greenspan L, Sullivan E, Eleeza J, Asiedu-Bekoe F, Amponsa-Achiano K, Ofori-Boadu L, Cadwell K, Ogunro A, Schaan M, Gebe N, Hammond E, Strachan M, Nanka-Bruce P, Balsara Z.   +22 more
europepmc   +1 more source

A report on Global Aging Initiative in Seoul

Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 2013
openaire   +3 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source