Results 101 to 110 of about 6,915,363 (238)

Global reporting initiative disclosure and corporate performance among GCC listed firms

open access: yesDiscover Sustainability
This study aims to investigate the impact of sustainability reporting quality on corporate performance. It also seeks to gain the deep insight into the useful of Global Reporting Initiative (GRI) to better sustainability reporting quality. The study uses
Waleed S. Alruwaili, Abeer Alsulami
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Chapter 8 – Global Reporting Initiative

open access: yes, 2020
This chapter provides an overview of the Global Reporting Initiative (GRI), which has become the most widely used framework for sustainability reporting in the world.
Rimmel, Gunnar; id_orcid
core  

Los estudios sobre los informes de sostenibilidad en América Latina

open access: yesRevista Enfoques de la Comunicación
Los informes, reportes o memorias de sostenibilidad son un mecanismo ampliamente utilizado en la contabilidad empresarial para la rendición de cuentas de una organización con respecto a sus acciones en los ámbitos sociales, económicos y medioambientales.
Diego Ortiz-Jaramillo, Irene Trelles
doaj  

A Review of Corporate Sustainability Reporting: Global and National scenario

open access: yesG-Journal of Environmental Science and Technology, 2013
Global concerns of climate change, poverty, human rights violations, and legal compliances have entailed corporate to pay attention towards social and environmental issues.
Ram Nayan Yadava, Bhaskar Sinha
doaj  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

The Rise of the Global Reporting Initiative (GRI) as a Case of Institutional Entrepreneurship

open access: yes, 2007
Since its conception in 1999, the Global Reporting Initiative (GRI) has rapidly become the leader among voluntary worldwide sustainability reporting systems.
Szejnwald Brown, Halina   +2 more
core   +2 more sources

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

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