Results 81 to 90 of about 6,915,363 (238)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Nível de disclosure nos relatórios de sustentabilidade em conformidade com o Global Reporting Initiative (GRI) = Level of disclosure in sustainability reports in compliance with Global Reporting Initiative (GRI)

open access: yesRevista Catarinense da Ciência Contábil, 2017
O objetivo do artigo é analisar o nível de disclosure nos relatórios de sustentabilidade em conformidade com o Global Reporting Initiative (GRI) nas empresas listadas na BM&FBovespa.
Daniela Di Domenico   +2 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Corporate Social Responsibility Disclousure, Media Attention, Woman on Board, and Firm Value

open access: yesJurnal ASET (Akuntansi Riset), 2019
. This study aims to examine the effect of corporate social responsibility disclosure on firm value with attention media and woman on board as a mediating variable.
Maria Natalia   +2 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Morocco's National Human Development Initiative

open access: yes, 2020
From 2000 to 2020, Morocco made significant strides in improving both its economic and its social status. Compared to the growth rates it maintained on average during the 1980s and 1990s, it increased its GDP growth rate and diversified its economy by
Global Delivery Initiative
core   +1 more source

Difusión de las memorias de sostenibilidad en Latinoamérica: análisis territorial y sectoria

open access: yesEstudios Gerenciales, 2015
En el presente artículo se plantean tres objetivos. En primer lugar, identificar cómo ha sido la difusión geo- gráfica y sectorial en Latinoamérica de los informes de sostenibilidad del tipo Global Reporting Initiative.
María del Mar Alonso-Almeida   +2 more
doaj  

A Comparative Review on Company Specific Determinants for Sustainability Reporting in United Kingdom (UK) and Malaysia

open access: yesSHS Web of Conferences, 2017
This study aims to comparatively assess the effects of company-specific variables on the level of corporate social responsibility (CSR) information disclosed in publicly-traded companies from United Kingdom (UK) and Malaysia. Content analysis was applied
Tong Xue Fa
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

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