Results 91 to 100 of about 7,934,994 (308)
IMF Working Papers, 2011 Current estimates of global poverty vary substantially across studies. In this paper we undertake a novel sensitivity analysis to highlight the importance of methodological choices in estimating global poverty. We measure global poverty using different data sources, parametric and nonparametric estimation methods, and multiple poverty lines.
Camelia Minoiu, Shatakshee Dhongde
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Sensitivity analysis and parameter estimation for evaluating the impact of water pollution on aquatic species [PDF]
Computational Ecology and SoftwareAquatic ecosystems are highly sensitive to changes in environmental conditions, making it essential to identify the key factors that influence the dynamics of species populations.
Christopher David Ngalya +2 more
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Sensitivity of building zones to potential global warming
, 2009 As global warming entails new conditions for the built environment, the thermal and energy performance of existing buildings, which are designed based on current weather data, may become unclear and remain a great concern.
Guan, Lisa, Lisa Guan
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
El ingeniero global en el desarrollo humano y sostenible [PDF]
, 2014 Obra formada per: Bloque A "El ingeniero global" (Vol. 1. La necesidad del ingeniero global. Vol. 2. Los elementos clave para afrontar la dimensión global de la ingeniería. Vol. 3.
Global Dimension in Engineering Education
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Mapping global sensitivity of cellular network dynamics: sensitivity heat maps and a global summation law [PDF]
Journal of The Royal Society Interface, 2008 The dynamical systems arising from gene regulatory, signalling and metabolic networks are strongly nonlinear, have high-dimensional state spaces and depend on large numbers of parameters. Understanding the relation between the structure and the function for such systems is a considerable challenge.
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Asymptotic Analysis for the Variance-Based Global Sensitivity Indices
Science and Technology of Nuclear Installations, 2012 We discuss the estimation of the uncertainty and sensitivity parameters for a model response under the assumption that the input variables are normally distributed and block-wise correlated with the covariance matrix, which is small in some norm.
Pavel M. Bokov
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