Results 181 to 190 of about 2,317,544 (334)

The application of global sensitivity analysis in the development of a physiologically based pharmacokinetic model for m-xylene and ethanol co-exposure in humans [PDF]

, 2015
George Loizou, Kevin McNally, Kate Jones, John Cocker   +3 more
openalex   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

Global Sensitivity Analysis with Mixtures: A Generalized Functional ANOVA Approach. [PDF]

Risk Anal, 2022
Borgonovo E, Li G, Barr J, Plischke E, Rabitz H.   +4 more
europepmc   +1 more source

Exploring the impact of forcing error characteristics on physically based snow simulations within a global sensitivity analysis framework [PDF]

, 2015
Mark S. Raleigh, Jessica D. Lundquist, Martyn Clark   +2 more
openalex   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

Global Sensitivity Analysis For Clinically Validated 1D Models of Fractional Flow Reserve. [PDF]

Annu Int Conf IEEE Eng Med Biol Soc, 2021
Tanade C, Feiger B, Vardhan M, Chen SJ, Leopold JA, Randles A.   +5 more
europepmc   +1 more source

Use of global sensitivity analysis and polynomial chaos expansion for interpretation of nonreactive transport experiments in laboratory‐scale porous media

, 2011
Noura Fajraoui, Fanilo Ramasomanana, Anis Younès, Thierry A. Mara, Philippe Ackerer, Alberto Guadagnini   +5 more
openalex   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Global Sensitivity Analysis via a Statistical Tolerance Approach. [PDF]

Eur J Oper Res, 2022
Curry S, Lee I, Ma S, Serban N.
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source