Results 51 to 60 of about 1,500,451 (153)

Overestimation of the effect of climatic warming on spring phenology due to misrepresentation of chilling

open access: yesNature Communications, 2020
Climate warming is advancing spring leaf unfolding, but it is also reducing the cold periods that many trees require to break winter dormancy. Here, the authors show that 7 of 12 current chilling models fail to account for the correct relationship ...
Huanjiong Wang   +6 more
doaj   +1 more source

Stabilising the global greenhouse: A simulation model [PDF]

open access: yes
This paper investigates the economic implications of a comprehensive approach to greenhouse policies that strives to stabilise the atmospheric concentration of greenhouse gases at an ecologicaliy determined threshold level.
Michaelis, Peter
core  

Experimentally based numerical models and numerical simulation with parameter identification of human lumbar FSUs in traction [PDF]

open access: yes, 2004
Numerical simulation of the behaviour of human lumbar spine segments, moreover, parameter-identification of the component organs of human lumbar FSUs are presented in traction therapies, by using FEM analysis. First, a simple 2D model, than a refined 2D
Kurutzné Kovács, Márta, Tornyos, A.
core  

Advancing Virtual Bioequivalence for Orally Administered Drug Products: Methodology, Real-World Applications and Future Outlook

open access: yesPharmaceuticals
Bioequivalence studies are pivotal in generic drug development wherein therapeutic equivalence is provided with an innovator product. However, bioequivalence studies represent significant complexities due to the interplay of multiple factors related to ...
Sivacharan Kollipara   +4 more
doaj   +1 more source

Global Health Simulation During Residency

open access: yesGlobal Pediatric Health, 2016
Resident participation in international health electives (IHEs) has been shown to be beneficial, yet not all residents have the opportunity to participate.
Jane R. Rosenman MD   +5 more
doaj   +1 more source

Modelling forest management within a global vegetation model (ORCHIDEE) [PDF]

open access: yes, 2008
Forests have an essential carbon function, removing each year about 20% of global anthropogenic CO2 emissions. Models have been designed to quantify the distribution of CO2 fluxes and ecosystem carbon dynamics at the global scale, but these global ...
Bellassen, Valentin   +4 more
core  

Towards Automatic Global Error Control: Computable Weak Error Expansion for the Tau-Leap Method

open access: yes, 2010
This work develops novel error expansions with computable leading order terms for the global weak error in the tau-leap discretization of pure jump processes arising in kinetic Monte Carlo models. Accurate computable a posteriori error approximations are
Karlsson, Jesper, Tempone, Raul
core   +1 more source

A bootstrapping method to optimize go/no‐go decisions from single‐arm, signal‐finding studies in oncology

open access: yesCPT: Pharmacometrics & Systems Pharmacology
Phase Ib trials are common in oncology development but often are not powered for statistical significance. Go/no‐go decisions are largely driven by observed trends in response data.
Raunak Dutta   +5 more
doaj   +1 more source

Socio-Economic Mechanisms to Coordinate the Internet of Services: The Simulation Environment SimIS [PDF]

open access: yes
Visions of 21st century information systems show highly specialized digital services and resources, which interact continuously and with a global reach.
Sebastian Hudert   +2 more
core  

Design Environments for Complex Systems [PDF]

open access: yes, 2003
The paper describes an approach for modeling complex systems by hiding as much formal details as possible from the user, still allowing verification and simulation of the model.
Priami, Corrado
core  

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