Results 21 to 30 of about 5,599,652 (237)

The second order modulus revisited: remarks, applications, problems

open access: yesJournal of Numerical Analysis and Approximation Theory
Several questions concerning the second order modulus of smoothness are addressed in this note. The central part is a refined analysis of a construction of certain smooth functions by Zhuk and its application to several problems in approximation theory,
Heiner Gonska, Ralitza K. Kovacheva
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

2019 - 2020 Digital Preservation Community Survey

open access: yes, 2020
The OPF (Open Preservation Foundation) conducted the 2019/2020 community survey between November 2019 and Februrary 2020 and the results provide a detailed picture of the digital preservation landscape today.
Open Preservation Foundation
core   +1 more source

Multivariate Perturbed Hyperbolic Tangent-Activated Singular Integral Approximation

open access: yesMathematics
Here we study the quantitative multivariate approximation of perturbed hyperbolic tangent-activated singular integral operators to the unit operator. The engaged neural network activation function is both parametrized and deformed, and the related kernel
George A. Anastassiou
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Approximation by boolean sums of positive linear operators VI: monotone approximation and global smoothness preservation

open access: yesJournal of Numerical Analysis and Approximation Theory, 1999
Not available.
H. H. Gonska, Jia -Ding Cao
doaj   +2 more sources

Best constants in preservation of global smoothness for Szász–Mirakyan operators

open access: yesJournal of Mathematical Analysis and Applications, 2008
For \(t>0\), the Szász-Mirakyan operator \(S_{t}\) is defined by \[ S_{t}f(x):=e^{-xt}\,\sum_{k=0}^{\infty}f\Big(\frac{k}{t}\Big)\frac{(tx)^{k}}{k!}, \quad x\geq 0, \] where \(f\) is any real function defined on \([0,\,\infty)\) such that \(S_{t}| f| (x)0, \quad C_{t}:=\sup_{\delta>0}C_{t}(\delta), \] where \[ w(f;\delta):=\sup\big\{| f(x)-f(y)| \,:x,y\
Adell, José A., Lekuona, Alberto
openaire   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

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