Results 21 to 30 of about 5,995,114 (237)

2019 - 2020 Digital Preservation Community Survey

, 2020
The OPF (Open Preservation Foundation) conducted the 2019/2020 community survey between November 2019 and Februrary 2020 and the results provide a detailed picture of the digital preservation landscape today.
Open Preservation Foundation
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Multivariate Perturbed Hyperbolic Tangent-Activated Singular Integral Approximation

Mathematics
Here we study the quantitative multivariate approximation of perturbed hyperbolic tangent-activated singular integral operators to the unit operator. The engaged neural network activation function is both parametrized and deformed, and the related kernel
George A. Anastassiou
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Approximation by boolean sums of positive linear operators VI: monotone approximation and global smoothness preservation

Journal of Numerical Analysis and Approximation Theory, 1999
Not available.
H. H. Gonska, Jia -Ding Cao
doaj   +2 more sources

Best constants in preservation of global smoothness for Szász–Mirakyan operators

Journal of Mathematical Analysis and Applications, 2008
For \(t>0\), the Szász-Mirakyan operator \(S_{t}\) is defined by \[ S_{t}f(x):=e^{-xt}\,\sum_{k=0}^{\infty}f\Big(\frac{k}{t}\Big)\frac{(tx)^{k}}{k!}, \quad x\geq 0, \] where \(f\) is any real function defined on \([0,\,\infty)\) such that \(S_{t}| f| (x)0, \quad C_{t}:=\sup_{\delta>0}C_{t}(\delta), \] where \[ w(f;\delta):=\sup\big\{| f(x)-f(y)| \,:x,y\
Adell, José A., Lekuona, Alberto
openaire   +2 more sources

On global smoothness preservation by Bernstein-type operators [PDF]

, 2015
We study global smoothness preservation of a function f by sequences of Bernstein-type operators with respect to a certain modulus of continuity of order two.
TALPĂU DIMITRIU, Maria
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source