Results 41 to 50 of about 880,355 (265)

What Do Global Metrics Tell Us about the World?

open access: yesSocial Sciences, 2019
There are now a wide variety of global indicators that measure different economic, political and social attributes of countries in the world. This paper seeks to answer two questions. First, what is the degree of overlap between these different measures?
John Rennie Short   +2 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Intellectual Property in the Context of Global Ethics [PDF]

open access: yesEastern European Journal of Regional Studies, 2021
Today we are the subjects and witnesses of the continuous development and transformation of society, which has made rapid leaps from modern to the informational and knowledge-based society.
Cristina LAZARIUC, Ecaterina LOZOVANU
doaj  

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The Global Professional [PDF]

open access: yesJournal of the National Council of Less Commonly Taught Languages, 2005
As educators in an increasingly global society, we realize that we need to train students-undergraduate and graduate-to live and work in a global environment.
Gilles Bousquet
doaj  

Digital higher education: a divider or bridge builder? Leadership perspectives on edtech in a COVID-19 reality

open access: yesInternational Journal of Educational Technology in Higher Education, 2021
The edtech community has promoted claims that digital education enhances access, learning, and collaboration. The COVID-19 pandemic tested these claims like never before, as higher education systems seemingly overnight had to move teaching online ...
Melissa Laufer   +6 more
doaj   +1 more source

The Fifth Season-Fastnacht/Carnival in Baden-Württemberg

open access: yesProceedings, 2022
This article discusses the Fastnacht Carnival celebrations in the village of Büßlingen in Baden-Württemberg (Southern Germany) which has both a rich local tradition and a multi-faceted history.
Irena Mostowicz, David Braunstein
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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