Results 71 to 80 of about 4,928,378 (308)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Pillars for Progress on the Right to Health: Harnessing the Potential of Human Rights Through a Framework Convention on Global Health [PDF]
, 2012 Ever more constitutions incorporate the right to health, courts continue to expand their right to health jurisprudence, and communities and civil society increasingly turn to the right to health in their advocacy.
Friedman, Eric A., Gostin, Lawrence O.
core +2 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Corporate social responsibility and banks [PDF]
, 2009 Article discussing ethical issues and matters of social responsibility surrounding turmoil in the capital markets, bank failures and government intervention. Article by Charles Chatterjee (Global Policy Institute, London Metropolitan University) and Anna
Chatterjee, Charles, Lefcovitch, Anna
core
Reimagining WHO: Leadership and Action for a New Director-General [PDF]
, 2017 Three candidates to be the next WHO Director-General remain: Tedros Adhanom Ghebreyesus, David Nabarro, and Sania Nishtar. The World Health Assembly’s ultimate choice will lead an Organization facing daunting internal and external challenges, from its ...
Friedman, Eric A., Gostin, Lawrence O.
core +2 more sources
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
The King's many bodies: the self-deconstruction of law's hierarchy [PDF]
, 2006 The article connects two strands of the recent sociolegal debate: (1) the empirical discovery of new forms of spontaneous law in die Course of globalization, and (2) the emergence of deconstructive theories of law that undermine the law's hierarchy.
Teubner, Gunther
core
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Civilizations for Global Society
Glocalism: Journal of Culture, Politics and Innovation, 2019 The fall of the Berlin Wall and the implosion of the Soviet Union created an effect comparable to culture shock in worldwide public opinion. These events were interpreted as an epochal change: a political revolution that opened a new era of human ...
Vittorio Cotesta
doaj +2 more sources
Globalized justice - fragmented justice. Human rights violations by "private" transnational actors [PDF]
, 2005 Plenarvortrag Weltkongress der Rechtsphilosophie und Sozialphilosophie, 24.-29. Mai, Granada 2005. S.a. die deutsche Fassung: "Die anonyme Matrix: Menschenrechtsverletzungen durch "private" transnationale Akteure".
Teubner, Gunther
core