Results 171 to 180 of about 8,988,058 (267)
Decoding Global Health Security Agenda
To stop disease outbreaks as quickly as possible, we must close gaps in prevention, detection and response. That is the vision of the Global Health Security Agenda (GHSA).US Goal: Protect up to 4 billion people in 30 countries in 5 ...
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Quantum-Inspired Fast Algorithm and Circuit Realization for Constrained Combinatorial Optimization Problem. [PDF]
Research (Wash D C)Chen H, Deng S, Chen T, Zhang X.
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
DSD-LI-PO: A Bioinspired Parrot Optimizer with Componentwise Swarm Hybridization and Contracted Lens Imaging Refinement for Constrained Engineering Optimization. [PDF]
Biomimetics (Basel)Qin M, Ding Y.
europepmc +1 more source
CDC Center for Global Health: Accomplishments: 2018
Publication date from document properties.CDC_CGH_Accomplishments_2018_508.pdfAdvancing Global Health Security -- Outbreaks and Emergency Response -- Ending the Burden of Diseases -- HIV Research, Policy, and Practice -- Vaccination Research for Action --
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Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
A Dynamic Optimization Algorithm Based on Energy Level Collaboration Mechanism. [PDF]
Entropy (Basel)Tang Q, Yang Y, Liu J.
europepmc +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Robust Broadband Differential Beamforming for Fully Steerable Linear Superarrays with Prescribed Nulls. [PDF]
Sensors (Basel)Wang Y, Zhang Y, Ding J, Ning J, Zhu Q.
europepmc +1 more source