Results 21 to 30 of about 782,077 (262)

Global Environmental Solutions Require Global Funding [PDF]

Eos, Transactions American Geophysical Union, 2008
As members of the next generation of environmental scientists, we are committed to conducting solutions‐oriented research on global environmental problems. In addition to the highly visible problem of climate change, we face global environmental threats such as biodiversity loss, worsening air quality, and limited food security and water availability ...
Anttila, Tatu, Bäck, Jaana, Barsanti, Kelley, Bilde, Merete, Boy, Michael, Carlton, Ann Marie, Ekman, Annica, Fry, Juliane, Glasius, Marianne, Hallar, Gannet, Heald, Colette, Hoyle, Christopher, Huff Hartz, Kara, Korhonen, Hannele, Petäjä, Tuukka, Petters, Markus, Rinne, Janne, Rosenoern, Thomas, Schurgers, Guy, Steiner, Allison, Sullivan, Amy, Sveningsson, Birgitta, Van Reken, Timothy, Wiedenmyer, Christine, Worton, David, Zardini, Alessandro Alessio   +25 more
openaire   +3 more sources

Global Continuation of Homoclinic Solutions [PDF]

Zeitschrift für Analysis und ihre Anwendungen, 2018
When extending bifurcation theory of dynamical systems to nonautonomous problems, it is a central observation that hyperbolic equilibria persist as bounded entire solutions under small temporally varying perturbations. In this paper, we abandon the smallness assumption and aim to investigate the global structure of the entity of all such bounded entire
Potzsche, Christian, Skiba, Robert
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

On the blow up time estimation to the Schrödinger equation

Lietuvos Matematikos Rinkinys, 2023
There is considered the Schrödinger equation ∂u/∂t= i Δu+ i|u|p , u, t > 0, with initial condition u(0, x)= u0(x),  x ∈ Rn, n = 1. We prove the existence of the u0(x) such, that the blow up time estimation increases if p increases in the intervale 4 < p
Gintaras Puriuškis
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

On a beam equation in Banach spaces

Electronic Journal of Qualitative Theory of Differential Equations, 2016
This paper is concerned with the existence and asymptotic behavior of solutions of the Cauchy problem for an abstract model for vertical vibrations of a viscous beam in Banach spaces.
Manuel Milla Miranda, Valdenilza Ferreira Silva, Ricardo Rodrigues Carvalho   +2 more
doaj   +1 more source