Results 101 to 110 of about 9,312,203 (384)

Viral infection dynamics in a spatial heterogeneous environment with cell-free and cell-to-cell transmissions

Mathematical Biosciences and Engineering, 2020
In this paper, we investigate a diffusive viral infection model in a spatial heterogeneous environment with two types of infection mechanisms and distinct dispersal rates for the susceptible and infected target cells. After establishing well-posedness of
Zongwei Ma, Hongying Shu
doaj   +1 more source

Emissions Pricing to Stabilize Global Climate [PDF]

SSRN Electronic Journal, 2011
In the absence of significant greenhouse gas (GHG) mitigation, many analysts project that atmospheric concentrations of species identified for control in the Kyoto protocol could exceed 1000 ppm (carbon-dioxide-equivalent) by 2100 from the current levels of about 435 ppm. This could lead to global average temperature increases of between 2.5 and 6°C by
Bosetti, Valentina, Paltsev, Sergey, Reilly, John M., Carraro, Carlo, Bosetti, Valentina, Paltsev, Sergey, Reilly, John M., Carraro, Carlo   +7 more
openaire   +7 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Stability analysis of an eco-epidemiological model incorporating a prey refuge

Nonlinear Analysis, 2010
The present paper deals with the problem of a predator-prey model incorporating a prey refuge with disease in the prey-population. We assume the predator population will prefer only infected population for their diet as those are more vulnerable ...
A. K. Pal, G. P. Samanta
doaj   +1 more source

Mathematical analysis of a human papillomavirus transmission model with vaccination and screening

Mathematical Biosciences and Engineering, 2020
We formulate a mathematical model to explore the transmission dynamics of human papillomavirus (HPV). In our model, infected individuals can recover with a limited immunity that results in a lower probability of being infected again.
Kai Zhang, Xinwei Wang , Hua Liu, Yunpeng Ji , Qiuwei Pan , Yumei Wei , Ming Ma   +6 more
doaj   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Scattering Cross Section and Stability of Global Monopoles

, 2017
We study the scattering of scalar waves propagating on the global monopole background. Since the scalar wave operator in this topological defect is not essentially self-adjoint, its solutions are not uniquely determined until a boundary condition at the ...
Barroso, V. S., Pitelli, J. P. M., Richartz, Maurício   +2 more
core   +1 more source

Density Dependent Predator Death Prevalence Chaos in a Tri-trophic Food Chain Model

Nonlinear Analysis, 2008
Ecological systems have all the properties to produce chaotic dynamics. To predict the chaotic behavior in an ecological system and its possible control mechanism is interesting.
M. Bandyopadhyay, S. Chatterjee, S. Chakraborty, J. Chattopadhyay   +3 more
doaj   +1 more source

Superspace and global stability in general relativity [PDF]

International Journal of Modern Physics D, 2017
A framework is developed enabling the global analysis of the stability of cosmological models using the local geometric characteristics of the infinite-dimensional superspace, i.e. using the generalized Jacobi equation reformulated for pseudo-Riemannian manifolds.
Gurzadyan, AV, Kocharyan, AA
openaire   +4 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source