Results 151 to 160 of about 730,247 (315)

Technology Spillovers and Stability of International Climate Coalitions [PDF]

Cooperation in international environmental agreements appears difficult to attain because of strong free-riding incentives. This paper explores how different technology spillover mechanisms among regions can influence the incentive structures to join and
Miyuki Nagashima, Rob Dellink
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Global Stability for an Endogenous-Reactivated Tuberculosis Model with Beddington-DeAngelis Incidence, Distributed Delay and Relapse. [PDF]

Qual Theory Dyn Syst, 2023
Sang Y, Zhang L, Song B, Zhang Y.
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Mapping the State of Financial Stability [PDF]

The paper uses the Self-Organizing Map for mapping the state of financial stability and visualizing the sources of systemic risks on a two-dimensional plane as well as for predicting systemic financial crises. The Self-Organizing Financial Stability Map (
Peltonen, Tuomas A., Sarlin, Peter
core   +2 more sources

Stability of Climate Coalitions in a Cartel Formation Game [PDF]

We empirically test stability of climate change coalitions with the STAbility of Coalitions model (STACO). The model comprises twelve world regions and captures important dynamic aspects of the climate change problem.
Michael Finus, Ekko van Ierland
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Global stability of an SAIRD epidemiological model with negative feedback. [PDF]

Adv Contin Discret Model, 2022
López-Cruz R.
europepmc   +1 more source

Reform of the Global Financial Architecture

This paper examines the implications of the global financialcrisis of 2007-10 for reform of the global financial architecture and identifies institutional and substantive reforms by organizations such as the IMF and Financial Stability Board.
Unknown
core  

Effect of Aspect Ratio on the Three-Dimensional Global Instability Analysis of Incompressible Open Cavity Flows

, 2011
The stability analysis of open cavity flows is a problem of great interest in the aeronautical industry. This type of flow can appear, for example, in landing gears or auxiliary power unit configurations.
Vassilios Theofilis, Elmer Gennaro, Gómez, Raquel, Theofilis, Vassilios, Paredes Gonzalez, Pedro, Pedro Paredes, Daniel Rodriguez, Theofilis, V., Tendero Ventanas, Juan Angel, Fernando Meseguer, Daniel Rodriguez Alvarez, Meseguer Garrido, Fernando, Rodríguez Álvarez, Daniel, Vicente Buendia, Javier de, Valero Sánchez, Eusebio, Marcello Medeiros, Gennaro, E. M., Paredes, P., Javier de Vicente, Eusebio Valero, J. Tendero, Gennaro, Elmer, Medeiros, M., Tendero, J. A., Gómez Carrasco, Francisco, Rodríguez, D., Medeiros, M. A. F.   +26 more
core   +1 more source