Results 131 to 140 of about 7,726,351 (314)
Global stability of an SAIRD epidemiological model with negative feedback. [PDF]
Adv Contin Discret Model, 2022 López-Cruz R.
europepmc +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Global stability and optimal control for a COVID-19 model with vaccination and isolation delays. [PDF]
Results Phys, 2022 Song H, Wang R, Liu S, Jin Z, He D.
europepmc +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
The global stability investigation of the mathematical design of a fractional-order HBV infection. [PDF]
J Appl Math Comput, 2022 Karaman B.
europepmc +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Global Stability of a Mumps Transmission Model with Quarantine Measure. [PDF]
Acta Math Appl Sin, 2021 Bai YZ, Wang XJ, Guo SB.
europepmc +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Global Stability of the Curzon-Ahlborn Engine with a Working Substance That Satisfies the van der Waals Equation of State. [PDF]
Entropy (Basel), 2022 Pacheco-Paez JC +3 more
europepmc +1 more source