Results 191 to 200 of about 1,185,877 (236)

Human Neutrophil Elastase and the Protein-Storm Axis: Reversible Synthetic Inhibitors in Inflammatory Disease. [PDF]

Molecules
Viglio S, Grignano MA, Gregorini M, Rampino T, Pietrocola G, Iadarola P.   +5 more
europepmc   +1 more source

Transfersomes with core and surface‐loaded NF‐κB p65 siRNA for enhanced transdermal transfection and effective treatment of psoriasis

BMEMat, EarlyView.
TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing, Yuhui Yang, Ziyi Zhao, Kai Lv, Yiran Shao, Zhi Zhang, Dong Ma   +6 more
wiley   +1 more source

Multi-heat keypoint incorporation in deep learning model to tropical cyclone centering and intensity classifying from geostationary satellite images. [PDF]

Sci Rep
Do TH, Phan ST, Du DT, Dang DQ, Mai KH, Hole LR.   +5 more
europepmc   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

Autophagy-ferroptosis crosstalk in sepsis: metabolic pathways, redox injury, and host-directed antioxidant nanomedicine. [PDF]

Front Immunol
Huang Y, Feng S, Wang J, Yi F, Gao Y.
europepmc   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

BMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu, Renwang Sheng, Mumin Cao, Ludvig J. Backman, Yucheng Gao, Hao Wang, Cheng Zhang, Jialin Chen, Wei Zhang, Yunfeng Rui   +9 more
wiley   +1 more source

Observed physical and biogeochemical variability due to tropical cyclone Mocha using glider observations in the Bay of Bengal. [PDF]

Sci Rep
Thangaprakash VP, Sureshkumar N, Srinivas KS, Chandramouli A, Theagarajan S, Rajasekhar Y, Kumar V, Kumar MR.   +7 more
europepmc   +1 more source

Nanoscale Imaging of Biological Tissues: Techniques, Challenges and Emerging Frontiers. [PDF]

Nanomaterials (Basel)
Kajla R, Leija-Cardenas R, Shivalingaiah MM, Shabbir MW, Ou Z.   +4 more
europepmc   +1 more source

The ZFP36-FTO axis is a key regulator of macrophage activation and a druggable therapeutic target of sepsis. [PDF]

iScience
Sarkar R, Wang L, Du J, Blackshear PJ, Li YC.   +4 more
europepmc   +1 more source