Results 101 to 110 of about 1,017,600 (345)

A simply connected surface of general type with p_g=0 and K^2=3

, 2007
Motivated by a recent result of Y. Lee and the second author[7], we construct a simply connected minimal complex surface of general type with p_g=0 and K^2=3 using a rational blow-down surgery and Q-Gorenstein smoothing theory.
Barth, Dongsoo Shin, Fintushel, Flenner, Heesang Park, Jongil Park, Manetti, Mumford, Nakayama, Ozsváth, Palamodov, Park, Symington, Wahl   +13 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Task Sharing in Global Cardiac Surgery: A Scoping Review

, 2022
Laura DiChiacchio, Alejandra Castro‐Varela, Dominique Vervoort, Amy G. Fiedler   +3 more
openalex   +1 more source

Improve OR-schedule to reduce number of required beds [PDF]

, 2012
After surgery most of the surgical patients have to be admitted in a ward in the hospital. Due to financial reasons and an decreasing number of available nurses in the Netherlands over the years, it is important to reduce the bed usage as much as ...
Bosch, Joel M., Essen, J. Theresia van, Hans, Erwin W., Houdenhoven, Mark van, Hurink, Johann L.   +4 more
core   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Cervical Deformity Patients Have Baseline Swallowing Dysfunction but Surgery Does Not Increase Dysphagia at 3 Months: Results From a Prospective Cohort Study. [PDF]

, 2019
Study designProspective cohort study.ObjectivesMost studies of dysphagia in the cervical spine have focused on a degenerative patient population; the rate of dysphagia following surgery for cervical deformity (CD) is unknown.
Ames, Christopher P, Bao, Hongda, International Spine Study Group (ISSG), Iyer, Sravisht, Kim, Han Jo, Klineberg, Eric O, Lafage, Virginie, Mundis, Gregory M, Neuman, Brian J, Passias, Peter, Protopsaltis, Themistocles S, Smith, Justin S   +11 more
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Successful task shifting: a mixed-methods cross-sectional evaluation of an emergency obstetric care program to increase access to cesarean sections in rural Nepal

Global Health Action
Background Direct obstetric causes of maternal mortality account for approximately 86% of all global maternal deaths. In Nepal, 12% of all deaths of women of reproductive age are due to preventable obstetric complications in significant part due to the ...
Rita Thapa Budhathoki, Abigail G. Knoble, Suresh Tamang, Bal Sundar Chansi Shrestha, Arpana BC Kalaunee, Indra Rai, Bikash Shrestha, Pravin Paudel, Ruma Rajbhandari, Archana Amatya   +9 more
doaj   +1 more source

Partnerships for Women's Health - Striving for Best Practice within the UN Global Compact / United Nations University Research Brief 1/2009 (www.unu.edu) [PDF]

Every minute, at least one woman dies from pregnancy and childbirth complications; a further 20 suffer injury, infection or disease. Despite medical advances, and years of policy declarations, this tragic situation remains particularly severe in ...
Kruesmann, Monika, Timmermann, Martina
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source