Results 41 to 50 of about 537,238 (257)

Global Surgery and Mercy Ships

open access: yesJournal of Oral Biology and Craniofacial Research, 2022
Two-thirds of the world population do not have access to safe, affordable and timely surgery. This global surgical crisis largely affects low and middle-income countries, and it will surpass the challenges created by communicable diseases. The barriers of access to surgery range from cost of surgery and patient transportation to availability and ...
Leo Cheng, Hilary Cheng, Gary Parker
openaire   +4 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Surgical Management and Reconstruction Training (SMART) Course for International Orthopedic Surgeons

open access: yesAnnals of Global Health, 2016
BackgroundThe burden of complex orthopedic trauma in low- and middle-income countries (LMICs) is exacerbated by soft-tissue injuries, which can often lead to amputations.
Hao-Hua Wu   +5 more
doaj   +1 more source

Building safe surgery knowledge and capacity in Cambodia: a mixed-methods evaluation of an innovative training and mentorship intervention

open access: yesGlobal Health Action, 2021
Background Working in partnership with the Cambodian Ministry of Health, the Safe Surgery 2020 initiative (SS2020) supports the prioritization of surgery and mobilization of resources to target limited workforce capacity.
Sehrish Bari   +14 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Ethical considerations in global surgery [PDF]

open access: yesJournal of British Surgery, 2019
Six key principles, seven ...
E, Steyn, J, Edge
openaire   +2 more sources

Building a Sustainable Global Surgical Program in an Academic Department of Surgery

open access: yesAnnals of Global Health, 2016
BackgroundGlobal surgery and volunteerism in surgery has gained significant interest in recent years for general surgery residents across the country.
Linda P. Zhang   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Role of mobile health on patient enrollment for cleft lip‐palate surgery: A comparative study using SMS blast text messaging in Zimbabwe

open access: yesLaryngoscope Investigative Otolaryngology, 2019
Background Patients' lack of awareness of available services is a significant barrier to delivering surgical care in resource‐limited settings. Short message service (SMS) text messaging is a potential means to disseminate this information in resource ...
Shekhar K. Gadkaree   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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