Results 61 to 70 of about 7,406,094 (340)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

The Task‐Sharing Path to Safe and Accessible Anaesthesia Care in India: The Role of Professional Associations in Health Policy Reform

Public Health Challenges
The worldwide anaesthesia workforce shortage is a concern and ‘shared responsibility’ for all the national or state anaesthetic societies and Ministries of Health.
Nobhojit Roy, Pranav Bhushan, Monali Mohan, Amal Paonaskar   +3 more
doaj   +1 more source

Measurements of Surgical Volume in Low- and Middle-Income Countries, a Systematic Review

Annals of Global Health, 2023
Background: Surgical volume is a surgical indicator that was described in the Lancet Commission on Global Surgery (LCoGS) and the World Bank World Development Indicators as an important metric for tracking the delivery of surgical care.
Ifeoluwa Shoyombo, Abraham Genetu, Lye-Yeng Wong, Muhammed Elhadi, Eric Twizeyimana, Grace Paidamoyo Gwini, Rutikanga William, Timothy Hall, Halimah Khalil, Siva Nyanamani Sandrasagran, Monica Langer   +10 more
doaj   +1 more source

Global Surgery Fellowships—An Investigation of Opportunities, Outcomes, and Applicants

Journal of hand and microsurgery, 2021
Following the Lancet Commission on Global Surgery in 2015, the Global Surgery Fellowships have risen in popularity, advertised as formalized opportunities for surgical trainees who have an interest in international surgical care. There is currently no up-
Elizabeth Davison, Satyendra K. Singh, B. Jemec   +2 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Surgical Management and Reconstruction Training (SMART) Course for International Orthopedic Surgeons

Annals of Global Health, 2016
BackgroundThe burden of complex orthopedic trauma in low- and middle-income countries (LMICs) is exacerbated by soft-tissue injuries, which can often lead to amputations.
Hao-Hua Wu, Kushal R. Patel, Amber M. Caldwell, R. Richard Coughlin, Scott L. Hansen, Joseph N. Carey   +5 more
doaj   +1 more source

World Health Assembly 73: A Step Forward for Global Surgery

Annals of Global Health, 2021
Member States at this year’s World Health Assembly 73 (WHA73), held virtually for the first time due to the COVID-19 pandemic, passed multiple resolutions that must be considered when framing efforts to strengthen surgical systems.
Gabrielle L Cahill, Makela C Stankey, C. McClain, Kee B. Park   +3 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Role of mobile health on patient enrollment for cleft lip‐palate surgery: A comparative study using SMS blast text messaging in Zimbabwe

Laryngoscope Investigative Otolaryngology, 2019
Background Patients' lack of awareness of available services is a significant barrier to delivering surgical care in resource‐limited settings. Short message service (SMS) text messaging is a potential means to disseminate this information in resource ...
Shekhar K. Gadkaree, Travis T. Tollefson, Jennifer C. Fuller, Faith C. Muchemwa, Aleck Gonga, David A. Shaye   +5 more
doaj   +1 more source

Building safe surgery knowledge and capacity in Cambodia: a mixed-methods evaluation of an innovative training and mentorship intervention

Global Health Action, 2021
Background Working in partnership with the Cambodian Ministry of Health, the Safe Surgery 2020 initiative (SS2020) supports the prioritization of surgery and mobilization of resources to target limited workforce capacity.
Sehrish Bari, Joseph Incorvia, Olivia Ahearn, Lem Dara, Swati Sharma, John Varallo, Victoria Smith, Monica Cainer, Cheav Samphy, Kith Rathamony, Ngin Kanora, Vithiea Dara, John G Meara, Virya Koy, Shehnaz Alidina   +14 more
doaj   +1 more source