Results 81 to 90 of about 749,476 (345)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Symptoms and causes of poverty in a rural Vietnamese commune: Does ethnicity matter?
Journal of Agriculture and Rural Development in the Tropics and Subtropics, 2014 This study uses data from a sample survey of 200 households drawn from a mountainous commune in Vietnam’s North Central Coast region to measure and explain relative poverty.
Van Le +3 more
doaj
Deep Trade Integration and North-South Participation in Global Value Chains
, 2022 Zarlasht M. Razeq
openalex +1 more source
WHY TRANSACTION COSTS IMPEDE SMALLHOLDER FARMERS’ PARTICIPATION INTO EXPORT ORGANIC MARKETS [PDF]
, 2014 s There have been growing trends of exports from countries dominated by smallholder agriculture to many of developed world (Kledal and Kwai, 2010). This shows that smallholders’ farmers development perspectives have gained interests in global markets ...
Karantininis, Kostas +5 more
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Global Value Chains and Employment Growth in Asia
Asian Development Review, 2019 This paper considers the sources of employment demand in Asian economies. Using data from the World–Input Output Database, I examine the relative importance of domestic and foreign demand in generating employment.
Neil Foster-McGregor
doaj +1 more source
Integrated in the global value chains – trade developments between Hungary and Asia [PDF]
, 2013 The international crisis which has been ongoing since 2008 caused severe recession and decrease of internal demand in the EU area. Therefore, European companies began to look for new markets outside the EU. In spite of the large distance, Asia can be one
Völgyi, Katalin, Éltető, Andrea
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Rents, Power and Governance in Global Value Chains
Journal of World-Systems Research, 2018 This paper addresses the generation of rents and the distribution of gains in the global operations of governed Global Value Chains (GVCs) and seeks to provide an architecture for analyzing the governance of GVCs.
Dennis Davis +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source