Results 91 to 100 of about 1,390,547 (346)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Potential impacts for monitoring sustainability: case study of hollow fiber membrane [PDF]

open access: yes, 2017
Sustainability level is a new indicator of quality and efficiency for product life cycle. Sustainability should be balanced among Triple Bottom Line (TBL) aspects namely environmental, economic and social elements.
Hemdi, Abdul Rahman   +3 more
core  

Arctic Soil Governs Whether Climate Change Drives Global Losses or Gains in Soil Carbon [PDF]

open access: yes, 2019
Key uncertainties in terrestrial carbon cycle projections revolve around the timing, direction, and magnitude of the carbon cycle feedback to climate change. This is especially true in carbon-rich Arctic ecosystems, where permafrost soils contain roughly
Bradford, MA   +4 more
core   +1 more source

Predicting the global warming potential of agro-ecosystems [PDF]

open access: yes, 2007
Abstract. Nitrous oxide, carbon dioxide and methane are the main biogenic greenhouse gases (GHG) contributing to the global warming potential (GWP) of agro-ecosystems. Evaluating the impact of agriculture on climate thus requires a capacity to predict the net exchanges of these gases in an integrated manner, as related to environmental conditions and ...
Lehuger, Simon   +5 more
openaire   +6 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

use natural gas consumption in 201Scenarios to decarbonize residential water heating in California [PDF]

open access: yes, 2017
This paper presents the first detailed long-term stock turnover model to investigate scenarios to decarbonize the residential water heating sector in California, which is currently dominated by natural gas.
Kammen, Daniel M   +2 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

The Big Burp: Where's the Proof? [PDF]

open access: yes
This lesson focuses on the possible release of methane from methane hydrates to the atmosphere and the potential impact of these releases on global warming, particularly how they might be involved with the Cambrian explosion and the Paleocene extinction ...

core  

Improving thermal conductivity of fired clay brick using sawdust waste [PDF]

open access: yes, 2018
The demand for energy efficient design and construction has become progressively important with the growing energy costs and increasing awareness on the effects of global warming.
Abas, Nor Haslinda   +5 more
core   +1 more source

Climate-Change Impact Potentials as an Alternative to Global Warming Potentials

open access: yesEnvironmental Research Letters, 2014
For policy applications, such as for the Kyoto Protocol, the climate-change contributions of different greenhouse gases are usually quantified through their global warming potentials. They are calculated based on the cumulative radiative forcing resulting from a pulse emission of a gas over a specified time period.
openaire   +2 more sources

Home - About - Disclaimer - Privacy