Results 111 to 120 of about 512,263 (263)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Are single global warming potential impact assessments adequate for carbon footprints of agri-food systems? [PDF]

open access: yesEnviron Res Lett, 2023
McAuliffe GA   +9 more
europepmc   +1 more source

Sustainable land use against the background of a growing wind power industry [PDF]

open access: yes
Among the measures discussed as remedies for CO2 emissions reduction renewable energies are prominent as they already provide marketable alternatives to fossil fuels.
Monsees, Jan, Ohl, Cornelia
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

The Big Burp: Where's the Proof? [PDF]

open access: yes
This lesson focuses on the possible release of methane from methane hydrates to the atmosphere and the potential impact of these releases on global warming, particularly how they might be involved with the Cambrian explosion and the Paleocene extinction ...

core  

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

Is There Really a Green Paradox? [PDF]

open access: yes
The Green Paradox states that, in the absence of a tax on CO2 emissions, subsidizing a renewable backstop such as solar or wind energy brings forward the date at which fossil fuels become exhausted and consequently global warming is aggravated.
Cees A. Withagen   +1 more
core  

Temperature, organic matter and the sustainability of aquatic systems [PDF]

open access: yes, 1995
Changes in sustainability of aquatic ecosystems are likely to be brought about by the global warming that has been widely predicted. In this article, the effects of water temperature on water-bodies (lakes, oceans and rivers) are reviewed followed by the
Wotton, Roger S
core  

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz   +11 more
wiley   +1 more source

Americans’ Global Warming Beliefs and Attitudes [PDF]

open access: yes, 2013
This report presents results from a national study of what Americans understand about how the climate system works, and the causes, impacts, and potential solutions to global warming.
Anthony Leiserowitz   +4 more
core   +1 more source

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