Results 101 to 110 of about 125,612 (305)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Globalisation, Inequality and Health [PDF]
As we suggested in a previous work (Borghesi and Vercelli, Sustainable globalisation, Ecological Economics, vol.44, n.1, 2003), the process of globalisation affects the sustainability of development mainly through three channels: economic growth ...
Alessandro Vercelli, Simone Borghesi
core
Villages and Globalisation: Introduction [PDF]
, 2017 A short introduction to the Villages and Globalisation issue of Architecture and Culture journal.
Ben Stringer, Stringer, B.
core +1 more source
Mapping migration capabilities worldwide
Comparative Migration StudiesThe complexity and abstract nature of capabilities may explain why research on migration aspirations is far more prevalent than studies on migration capabilities, and why clear conceptualizations and operationalizations of migration capabilities remain ...
Naiara Rodríguez-Peña
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
GLOBALISATION AND EXPORT COMPETITIVENESS: A THEORETICAL APPROACH [PDF]
Over the past two decades, globalisation has given a boost to world trade, has grown one and a half times faster than world output, and the difference has even been considerably higher in recent years as world trade growth accelerated very strongly ...
GIURGIU Adriana, DODESCU Anca
core
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Globalisation of R&D and Technology Markets - Trends, Motives, Consequences
, 2022 S.37-78On the treshold of the 21st century, an intensive debate about globalisation of R&D and technology markets is of cucial importance. Globalisation will carry on changing the framework for company strategies and subsequently for public policies ...
Reger, G. +2 more
core +1 more source